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Steroidal Saponins From Solanum Nigrum

Xinlan Zhou, Xiangjiu He, Guanghui Wang, Hao Gao, Guangxiong Zhou, Wencai Ye, Xinsheng Yao

J Nat Prod. 2006 Aug;69(8):1158-63.

PMID: 16933867

Abstract:

Six new steroidal saponins, solanigrosides C-H (2-7), and one known saponin, degalactotigonin (1), were isolated from the whole plant of Solanum nigrum. Their chemical structures were elucidated using spectroscopic analysis, chemical degradation, and derivatization. All seven compounds were tested for their cytotoxicity using four human tumor cell lines (HepG2, NCI-H460, MCF-7, SF-268). Only compound 1 was cytotoxic, with IC50 values of 0.25-4.49 microM.

Chemicals Related in the Paper:

Catalog Number Product Name Structure CAS Number Price
AP39941510 Degalactotigonin Degalactotigonin 39941-51-0 Price
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