Chromatography Standards Line

In modern analytical testing, chromatography is widely used in fields such as food safety, environmental monitoring, and pharmaceutical analysis due to its efficiency, sensitivity, and accuracy. As a core component of chromatographic analysis, chromatography standards directly affect the accuracy and reproducibility of test results. As a professional supplier of analytical standards, we are committed to providing customers with high-purity, traceable chromatography standards to support the smooth progress of scientific research and quality control.

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What Are Chromatography Standards?

Chromatography standards are essential reference materials used in instruments such as gas chromatography (GC), high-performance liquid chromatography (HPLC), and mass spectrometry systems (GC-MS, LC-MS) for qualitative and quantitative analysis. Their chemical composition, purity, and concentration are strictly controlled, making them crucial for building calibration curves, identifying target compounds, method validation, and instrument calibration.

Chromatography Techniques and Matching Standards

Gas Chromatography (GC) Standards

Suitable for analyzing volatile and thermally stable compounds

Liquid Chromatography (HPLC) Standards

Suitable for polar, thermally unstable, or high molecular weight compounds

Mass Spectrometry Coupled (GC-MS, LC-MS) Standards

Used for trace analysis and complex sample matrices

Ion Chromatography (IC) Standards

Used for the separation and analysis of inorganic anions and cations

Chromatography Standards We Offer

To meet diverse analytical demands, our company provides a wide range of certified reference standards, systematically categorized by application area to support various chromatography and analytical techniques.

Certified Reference Material for Chromatography

Pharmaceutical and Drug Standards

Column & Instrument Performance Test Mixes

Environmental Standards

Life Sciences Standards

Forensic and Veterinary Standards

Food & Beverage Standards

Petrochemical Standards

Clinical Standards

Colors

Custom Standards Services

We provide customized services according to customer requirements, including:

Single-component standards with specified structure, purity, or concentration
Multi-component mixed standards
Standards in specific matrices (e.g., blood, urine, soil, water samples)

High Purity and Accurate Concentration

Our standards reach purities over 98% and are precisely formulated to ensure stable and reliable analytical data, suitable for high-demand research and QC labs.

Traceability and Compliance

All standards are provided with complete quality documentation, including COA, MSDS, and safety transport labels. Products comply with international quality standards such as ISO 17034 and ISO 9001.

Flexible Packaging

Available in various specifications from micro quantities (μg, mg) to standard liquid packaging (mL) to suit different lab needs and budget constraints.

Secure Storage and Transport

We use high-seal, light- and moisture-resistant packaging. Some products are compatible with cold chain logistics to ensure maximum stability and integrity during shipping.

Technical and Support Services

Recommendation

Method recommendations for chromatography standards

Calibration Support

Assistance in establishing calibration curves and analytical protocols

Documents

SOP documents, method downloads, and technical literature

Troubleshooting

Dedicated technical support team for troubleshooting

Quality Control and Example Test Reports

Each batch of standards is validated by multiple testing methods, including:

Nuclear Magnetic Resonance (NMR)
Mass Spectrometry (MS)
GC/HPLC Chromatography
Ultraviolet Spectroscopy (UV)

Example quality reports are available on product pages or upon request.

What Success Stories Can We Share?

Discover how our products are applied in real-world scenarios through our case studies.

Case 1: Third-Party Food Testing Lab Achieves Accurate Detection of Aflatoxins

Customer Background:

A specialized third-party food testing laboratory focused on providing quantitative analysis of mycotoxins for food companies and regulators.

Challenge:

When detecting aflatoxins (B1, B2, G1, G2) using HPLC-FLD, the lab faced issues with inconsistent purity and fluctuating response values between batches, severely affecting quantification precision and method reproducibility.

Product Purchased:

Our high-purity aflatoxins mix standard (B1 [CAS: 1162-65-8], B2 [CAS: 7220-81-7], G1 [CAS: 1165-39-5], G2 [CAS: 7241-98-7]) at 1 µg/mL in acetonitrile:water (1:1), with complete COA and storage guidelines.

Results:

After use in method development and routine analysis, the calibration showed excellent linearity (R² > 0.999), sensitivity increased by ~20%, and detection fully met food safety limits. The lab praised the stability and consistency and adopted the product for long-term use.

Case 2: Pharmaceutical Company Improves API QC Efficiency with Amino Acid Standards

Customer Background:

A large pharmaceutical company developing and producing amino acid-based APIs, requiring quality control of various free amino acids.

Challenge:

The original setup used individually sourced single-component standards, which were cumbersome, unstable, and introduced cumulative errors, reducing UPLC-MS/MS method efficiency.

Product Purchased:

Our amino acid mixed standard solution (Amino Acid Mix Standard Solution), containing 17 common amino acids at 250 µmol/L each, in 0.1 N HCl, 5 mL/vial, product number AC-AAS-17MIX, with full analytical and traceability documentation.

Results:

Successfully used for UPLC-MS/MS method development and batch QC. The method showed excellent repeatability (RSD < 2%) and ~30% increase in efficiency, meeting ICH Q2 (R1) validation standards. The customer highly valued the component uniformity and ease of use, significantly optimizing their API quality monitoring workflow.

Case 3: Environmental Lab Enhances Surface Water Monitoring with Organochlorine Pesticide Standards

Customer Background:

An environmental lab responsible for monitoring persistent organic pollutants (POPs) in surface waters.

Challenge:

For GC-ECD detection of organochlorine pesticides (e.g., DDT, γ-BHC) at ng/L levels, the lab required high-purity, interference-free, homogenous standards to ensure data accuracy and traceability.

Product Purchased:

Our organochlorine pesticide mix standard, including 12 representative compounds (α-, β-, γ-, δ-BHC; o,p'-DDT, p,p'-DDT, etc.), at 100 µg/mL in isooctane, 2 mL vial, compliant with EPA Method 8081A.

Results:

Combined with SPE and GC-ECD methods, the standard enabled accurate detection of pg/mL pollutants in surface water. All detection limits exceeded technical guidelines. The project passed third-party validation, and the customer now uses the product in routine monitoring.

Ordering Process & Service Commitment

How to Order

Online selection and order
Email/phone consultation for custom needs
One-on-one support from technical engineers

Lead Time

Regular standards ship within 1–2 business days
Custom standard lead time confirmed after technical evaluation

After-Sales Service

Full refund or replacement for quality issues
Guidance on usage, technical support, and documentation updates

Frequently Asked Questions (FAQ)

Q1: How to choose the appropriate chromatographic standard for method development?

When selecting a standard, consider the structural characteristics of the target analyte, the expected sample matrix, the detection method (GC, HPLC, LC-MS, etc.), and regulatory requirements. Priority should be given to high-purity standards of structurally similar or homologous compounds. For trace or metabolite analysis, the use of isotopically labeled or stable internal standards is recommended to enhance quantification reliability.

Q2: Why do response values differ slightly between different batches of standards?

Such differences may result from calibration errors, minor purity variations, or the effects of transportation and storage conditions. Each batch of our standards is recalibrated and provided with a Certificate of Analysis (COA). We recommend re-establishing or validating the calibration curve when using a new batch to ensure data consistency and traceability.

Q3: What should be considered when using standards in LC-MS analysis?

When using standards in LC-MS, especially for trace analysis, solvent compatibility (e.g., avoiding high-salt solvents), ion suppression effects, and the absence of interfering peaks must be considered. It is recommended to prepare standards in MS-grade solvents and filter them to remove particulates. If using internal standard methods, ensure the internal standard does not co-elute or conflict in mass-to-charge ratio with the analyte.

Q4: Can components in multi-component mixed standards react with each other?

This depends on the chemical properties of each component and the solvent used for preparation. We assess the stability and compatibility of components before preparing mixed standards to avoid degradation or cross-reactions. For customers preparing their own mixtures, we recommend small-scale stability testing or consulting us for formulation advice.

Q5: Will the concentration of standards change during long-term storage? How to monitor it?

Some standards may undergo concentration shifts due to volatilization, oxidation, or hydrolysis, especially under high temperature or humidity. It is recommended to periodically recalibrate the method using known standards or monitor trends via retention time and peak area ratios. We recommend storing standards in a cool, dark place, recording the opening date, and confirming stability if used beyond the recommended period.

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Chromatography Standards Line

What Are Chromatography Standards?

Chromatography Techniques and Matching Standards

Gas Chromatography (GC) Standards

Liquid Chromatography (HPLC) Standards

Mass Spectrometry Coupled (GC-MS, LC-MS) Standards

Ion Chromatography (IC) Standards

Chromatography Standards We Offer

Custom Standards Services

Product Advantages

High Purity and Accurate Concentration

Traceability and Compliance

Flexible Packaging

Secure Storage and Transport

Technical and Support Services

Quality Control and Example Test Reports

What Success Stories Can We Share?

Case 1: Third-Party Food Testing Lab Achieves Accurate Detection of Aflatoxins

Case 2: Pharmaceutical Company Improves API QC Efficiency with Amino Acid Standards

Case 3: Environmental Lab Enhances Surface Water Monitoring with Organochlorine Pesticide Standards

Ordering Process & Service Commitment

Frequently Asked Questions (FAQ)

Need Help or Have a Question?