CAS 704-00-7 1,2-Diacetylbenzene - Analytical Products / Alfa Chemistry

CAT	AP704007
CAS	704-00-7
MDL Number	MFCD00008733
Molecular Weight	162.19
EC Number	211-877-6
InChI Key	LVQFKRXRTXCQCZ-UHFFFAOYSA-N
REAXYS Number	1862907

Description	99%
Solubility	dichloromethane: soluble 50 mg/mL, clear, colorless to yellow
Assay	99%
BP	110 °C/0.1 mmHg (lit.)
Linear Formula	C6H4(COCH3)2
MP	39-41 °C (lit.)
Size	100MG, 500MG

1

1,2-diacetylbenzene, the Neurotoxic Metabolite of a Chromogenic Aromatic Solvent, Induces Proximal Axonopathy

M S Kim, M I Sabri, V H Miller, R J Kayton, D A Dixon, P S Spencer

Toxicol Appl Pharmacol. 2001 Dec 1;177(2):121-31.

PMID: 11740911

1

Amino Acid and Protein Targets of 1,2-diacetylbenzene, a Potent Aromatic Gamma-Diketone That Induces Proximal Neurofilamentous Axonopathy

Min-Sun Kim, Seyed B Hashemi, Peter S Spencer, Mohammad I Sabri

Toxicol Appl Pharmacol. 2002 Aug 15;183(1):55-65.

PMID: 12217642

1

Axonopathy-inducing 1,2-diacetylbenzene Forms Adducts With Motor and Cytoskeletal Proteins Required for Axonal Transport

Mohammad I Sabri, Seyed B Hashemi, Michael R Lasarev, Peter S Spencer

Neurochem Res. 2007 Dec;32(12):2152-9.

PMID: 17577667

1

Cytotoxicity of 1,2-diacetylbenzene in Human Neuroblastoma SHSY5Y Cells Is Mediated by Oxidative Stress

Min-Sun Kim, Min Kyeong Kim, Kwang Seok Kim, Jae Heun Chung, So Jung Kim, Jung Hye Kim, Jae-Ryong Kim, Jaewon Lee, Byung Pal Yu, Hae Young Chung

Toxicology. 2008 Jan 14;243(1-2):216-23.

PMID: 18063464

1

Organic Solvent Metabolite, 1,2-diacetylbenzene, Impairs Neural Progenitor Cells and Hippocampal Neurogenesis

Min-Sun Kim, Hee Ra Park, Hae Young Chung, Hyung Sik Kim, Byung Pal Yu, Hee-Sun Yang, Jaewon Lee

Chem Biol Interact. 2011 Nov 15;194(2-3):139-47.

PMID: 22020177