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1,5-Isoquinolinediol

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For Research Use Only | Not For Clinical Use
CATAP5154029-A
CAS5154-02-9
MDL NumberMFCD00006900
Molecular Weight161.16
InChI KeyLFUJIPVWTMGYDG-UHFFFAOYSA-N
Description≥98% (HPLC), powder
SolubilityDMSO: 20 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 100MG
Storage Conditions2-8°C
1

1,5-isoquinolinediol Increases the Frequency of Gene Targeting by Homologous Recombination in Mouse Fibroblasts

Alexandre Semionov, Denis Cournoyer, Terry Y K Chow

Biochem Cell Biol. 2003 Feb;81(1):17-24.

PMID: 12683632

1

Inhibition of NOS-2 Induction in LPS-stimulated J774.2 Cells by 1, 5-isoquinolinediol, an Inhibitor of PARP

R Olszanecki, A Gebska, J Jawień, A Jakubowski, R Korbut

J Physiol Pharmacol. 2006 Mar;57(1):109-17.

PMID: 16601319

1

Pharmacogenomic Analysis Indicates Potential of 1,5-isoquinolinediol as a Universal Anti-Aging Agent for Different Tissues

Mi Sung Park, Joon-Seok Choi, Wan Lee, Yoon Jung Yang, Juhee Kim, Gun-Joo Lee, Sang Soo Kim, Seong Hoon Park, Sung Chul Kim, Jin Woo Choi

Oncotarget. 2015 Jul 10;6(19):17251-60.

PMID: 25980498

1

Reversal of Neurobehavioral and Neurochemical Alterations in STZ-induced Diabetic Rats by FeTMPyP, a Peroxynitrite Decomposition Catalyst and 1,5-Isoquinolinediol a poly(ADP-ribose) Polymerase Inhibitor

Ashok Jangra, Ashok Kumar Datusalia, Shyam Sunder Sharma

Neurol Res. 2014 Jul;36(7):619-26.

PMID: 24620961

1

The Poly(ADP-Ribose)Polymerase-1 Inhibitor 1,5-Isoquinolinediol Attenuate Diabetes-Induced NADPH Oxidase-Derived Oxidative Stress in Retina

Ghulam Mohammad, Saleh Hamed Alrashed, Abdullah Ibrahim Almater, Mohammad Mairaj Siddiquei, Ahmed M Abu El-Asrar

J Ocul Pharmacol Ther. 2018 Sep;34(7):512-520.

PMID: 29912609

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