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1-EBIO

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For Research Use Only | Not For Clinical Use
CATAP10045451
CAS10045-45-1
Structure
MDL NumberMFCD00005715
Molecular Weight162.19
EC Number233-148-1
InChI KeyCXUCKELNYMZTRT-UHFFFAOYSA-N
Description≥98% (HPLC)
SolubilityDMSO: ≥20 mg/mL
Assay≥98% (HPLC)
Formpowder
Size10MG, 50MG
Storage Conditionsroom temp
1

1-EBIO Stimulates Cl- Secretion by Activating a Basolateral K+ Channel in the Mouse Jejunum

K L Hamilton, L Meads, A G Butt

Pflugers Arch. 1999 Dec;439(1-2):158-66.

PMID: 10651013

1

Activation of K(+) Channel by 1-EBIO Rescues the Head and Neck Squamous Cell Carcinoma Cells From Ca(2+) Ionophore-Induced Cell Death

Ming Zhe Yin, Seok-Woo Park, Tae Wook Kang, Kyung Soo Kim, Hae Young Yoo, Junho Lee, J Hun Hah, Myung Hun Sung, Sung Joon Kim

Korean J Physiol Pharmacol. 2016 Jan;20(1):25-33.

PMID: 26807020

1

Chlorzoxazone or 1-EBIO Increases Na(+) Absorption Across Cystic Fibrosis Airway Epithelial Cells

L Gao, J R Yankaskas, C M Fuller, E J Sorscher, S Matalon, H J Forman, C J Venglarik

Am J Physiol Lung Cell Mol Physiol. 2001 Nov;281(5):L1123-9.

PMID: 11597903

1

In Vivo Characterisation of the Small-Conductance KCa (SK) Channel Activator 1-ethyl-2-benzimidazolinone (1-EBIO) as a Potential Anticonvulsant

Neil J Anderson, Scott Slough, William P Watson

Eur J Pharmacol. 2006 Sep 28;546(1-3):48-53.

PMID: 16925994

1

The K+ Channel Opener 1-EBIO Potentiates Residual Function of Mutant CFTR in Rectal Biopsies From Cystic Fibrosis Patients

Eva K Roth, Stephanie Hirtz, Julia Duerr, Daniel Wenning, Irmgard Eichler, Hans H Seydewitz, Margarida D Amaral, Marcus A Mall

PLoS One. 2011;6(8):e24445.

PMID: 21909392

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