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1-Phenylbiguanide

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For Research Use Only | Not For Clinical Use
CATAP102023
CAS102-02-3
Structure
MDL NumberMFCD00179077
Molecular Weight177.21
EC Number202-998-5
InChI KeyCUQCMXFWIMOWRP-UHFFFAOYSA-N
Description98%
Solubilityalcohol: freely soluble; water: freely soluble
Assay98%
Linear FormulaC6H5NHC(=NH)NHC(=NH)NH2
MP135-142 °C (lit.)
Size25G
1

Activation of 5-HT3 Receptor by 1-phenylbiguanide Increases Dopamine Release in the Rat Nucleus Accumbens

J P Chen, H M van Praag, E L Gardner

Brain Res. 1991 Mar 15;543(2):354-7.

PMID: 1711914

1

Behavioral Effects of the 5-hydroxytryptamine3 Receptor Agonists 1-phenylbiguanide and M-Chlorophenylbiguanide in Rats

G A Higgins, N Joharchi, E M Sellers

J Pharmacol Exp Ther. 1993 Mar;264(3):1440-9.

PMID: 8450478

1

Inhibitory Effects of 2-guanidinebenzimidazole and 1-phenylbiguanide on Gastric Acid Secretion in Rats

A Pinelli, R Colombo, S Trivulzio, F Berti, O Tofanetti, B R Caimi

Arzneimittelforschung. 1984;34(8):890-4.

PMID: 6093826

1

Several Receptor Subtypes Contribute to 5-hydroxytryptamine-induced Secretion by Rat Ileum In-Vitro

J Hardcastle, P T Hardcastle

J Pharm Pharmacol. 1997 Nov;49(11):1114-20.

PMID: 9401948

1

Stereochemistry of Serotonin Receptor Ligands From Crystallographic Data. Crystal Structures of NAN-190.HBr, 1-phenylbiguanide, MDL 72222 and mianserin.HCl and Selectivity Criteria Towards 5-HT1, 5-HT2, and 5-HT3 Receptor Subtypes

A Dalpiaz, V Ferretti, P Gilli, V Bertolasi

Acta Crystallogr B. 1996 Jun 1;52 ( Pt 3):509-18.

PMID: 8767764

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