10074-G5

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For Research Use Only | Not For Clinical Use
CATAP413611935-A
CAS413611-93-5
Structure
MDL NumberMFCD00576774
Molecular Weight332.31
InChI KeyKMJPYSQOCBYMCF-UHFFFAOYSA-N
Description≥98% (HPLC)
SolubilityDMSO: >10 mg/mL
Assay≥98% (HPLC)
Colorred
Formpowder
Size5MG, 25MG
Storage Conditionsroom temp

1c-Myc Inhibitor 10074-G5 Induces Murine and Human Hematopoietic Stem and Progenitor Cell Expansion and HDR Modulator Rad51 Expression

Merve Aksoz, Esra Albayrak, Galip Servet Aslan, Raife Dilek Turan, Lamia Yazgi Alyazici, Pınar Siyah, Emre Can Tuysuz, Serli Canikyan, Dogacan Yucel, Neslihan Meric, Zafer Gulbas, Fikrettin Sahin, Fatih Kocabas

Curr Cancer Drug Targets. 2019;19(6):479-494.

PMID: 30182856

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1Disruption of Myc-Max Heterodimerization With Improved Cell-Penetrating Analogs of the Small Molecule 10074-G5

Huabo Wang, Jay Chauhan, Angela Hu, Kelsey Pendleton, Jeremy L Yap, Philip E Sabato, Jace W Jones, Mariarita Perri, Jianshi Yu, Erika Cione, Maureen A Kane, Steven Fletcher, Edward V Prochownik

Oncotarget. 2013 Jun;4(6):936-47.

PMID: 23801058

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1Erratum: Disruption of Myc-Max Heterodimerization With Improved Cell-Penetrating Analogs of the Small Molecule 10074-G5

Huabo Wang, Jay Chauhan, Angela Hu, Kelsey Pendleton, Jeremy L Yap, Philip E Sabato, Jace W Jones, Mariarita Perri, Jianshi Yu, Erika Cione, Maureen A Kane, Steven Fletcher, Edward V Prochownik

Oncotarget. 2018 Oct 12;9(80):35196.

PMID: 30416689

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1In Vitro Cytotoxicity and in Vivo Efficacy, Pharmacokinetics, and Metabolism of 10074-G5, a Novel Small-Molecule Inhibitor of c-Myc/Max Dimerization

Dana M Clausen, Jianxia Guo, Robert A Parise, Jan H Beumer, Merrill J Egorin, John S Lazo, Edward V Prochownik, Julie L Eiseman

J Pharmacol Exp Ther. 2010 Dec;335(3):715-27.

PMID: 20801893

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1Pharmacophore Identification of c-Myc Inhibitor 10074-G5

Jeremy L Yap, Huabo Wang, Angela Hu, Jay Chauhan, Kwan-Young Jung, Robert B Gharavi, Edward V Prochownik, Steven Fletcher

Bioorg Med Chem Lett. 2013 Jan 1;23(1):370-4.

PMID: 23177256

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