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14-Deoxy-11,12-didehydroandrographolide

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For Research Use Only | Not For Clinical Use
CATAP42895589
CAS42895-58-9
Structure
MDL NumberMFCD07778081
Molecular Weight332.43
InChI KeyXMJAJFVLHDIEHF-CRBRZBHVSA-N
Descriptionanalytical standard
Assay≥95% (HPLC)
Formneat; gas chromatography (GC): suitable
Gradeanalytical standard
Size5MG
1

14-Deoxy-11,12-didehydroandrographolide Induces DDIT3-dependent Endoplasmic Reticulum Stress-Mediated Autophagy in T-47D Breast Carcinoma Cells

Heng Kean Tan, Tengku Sifzizul Tengku Muhammad, Mei Lan Tan

Toxicol Appl Pharmacol. 2016 Jun 1;300:55-69.

PMID: 27049118

1

14-Deoxy-11,12-didehydroandrographolide Suppresses Adipogenesis of 3 T3-L1 Preadipocytes by Inhibiting CCAAT/enhancer-binding Protein β Activation and AMPK-mediated Mitotic Clonal Expansion

Chien-Chun Li, Chih-Ching Yen, Ciou-Ting Fan, Wei-Ting Chuang, Chin-Shiu Huang, Haw-Wen Chen, Chong-Kuei Lii

Toxicol Appl Pharmacol. 2018 Nov 15;359:82-90.

PMID: 30248417

1

Andrographolide and 14-deoxy-11, 12-didehydroandrographolide Inhibit Cytochrome P450s in HepG2 Hepatoma Cells

Jer Ping Ooi, Masanori Kuroyanagi, Shaida Fariza Sulaiman, Tengku Sifzizul Tengku Muhammad, Mei Lan Tan

Life Sci. 2011 Feb 28;88(9-10):447-54.

PMID: 21219911

1

Bioavailability of the Diterpenoid 14-deoxy-11,12-didehydroandrographolide in Rats and Up-Regulation of Hepatic Drug-Metabolizing Enzyme and Drug Transporter Expression

Chih-Ching Yen, Yun-Ta Liu, Ying-Jyan Lin, Ya-Chen Yang, Chien-Chih Chen, Hsien-Tsung Yao, Haw-Wen Chen, Chong-Kuei Lii

Phytomedicine. 2019 Aug;61:152841.

PMID: 31035043

1

Synthesis of 14-deoxy-11,12-didehydroandrographolide Analogues as Potential Cytotoxic Agents for Cholangiocarcinoma

Sudarat Sombut, Rada Bunthawong, Uthaiwan Sirion, Teerapich Kasemsuk, Pawinee Piyachaturawat, Kanoknetr Suksen, Apichart Suksamrarn, Rungnapha Saeeng

Bioorg Med Chem Lett. 2017 Dec 1;27(23):5139-5143.

PMID: 29097170

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