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2,5-Dimethyl-celecoxib

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For Research Use Only | Not For Clinical Use
CATAP457639268
CAS457639-26-8
Structure
MDL NumberMFCD19443858
Molecular Weight395.40
InChI KeyNTFOSUUWGCDXEF-UHFFFAOYSA-N
1

2,5-Dimethyl-Celecoxib Extends Drosophila Life Span via a Mechanism That Requires Insulin and Target of Rapamycin Signaling

Qi Wu, Ting Lian, Xiaolan Fan, Chaochun Song, Uma Gaur, Xueping Mao, Deying Yang, Matthew D W Piper, Mingyao Yang

J Gerontol A Biol Sci Med Sci. 2017 Oct 1;72(10):1334-1341.

PMID: 28025308

1

2,5-Dimethyl-celecoxib Inhibits Cell Cycle Progression and Induces Apoptosis in Human Leukemia Cells

Cyril Sobolewski, Jiyun Rhim, Noémie Legrand, Florian Muller, Claudia Cerella, Fabienne Mack, Sébastien Chateauvieux, Jeoung-Gyun Kim, Ah-Young Yoon, Kyu-Won Kim, Mario Dicato, Marc Diederich

J Pharmacol Exp Ther. 2015 Nov;355(2):308-28.

PMID: 26330537

1

Antiangiogenic Activities of 2,5-dimethyl-celecoxib on the Tumor Vasculature

Jenilyn J Virrey, Zhi Liu, Hee-Yeon Cho, Adel Kardosh, Encouse B Golden, Stan G Louie, Kevin J Gaffney, Nicos A Petasis, Axel H Schönthal, Thomas C Chen, Florence M Hofman

Mol Cancer Ther. 2010 Mar;9(3):631-41.

PMID: 20197398

1

Celecoxib Exerts Protective Effects in the Vascular Endothelium via COX-2-independent Activation of AMPK-CREB-Nrf2 Signalling

Fahad Al-Rashed, Damien Calay, Marie Lang, Clare C Thornton, Andrea Bauer, Allan Kiprianos, Dorian O Haskard, Anusha Seneviratne, Joseph J Boyle, Alex H Schönthal, Caroline P Wheeler-Jones, Justin C Mason

Sci Rep. 2018 Apr 19;8(1):6271.

PMID: 29674687

1

Dimethyl Celecoxib as a Novel Non-Cyclooxygenase 2 Therapy in the Treatment of Non-Small Cell Lung Cancer

Leah M Backhus, Nicos A Petasis, Jasim Uddin, Axel H Schönthal, Robert D Bart, Yuanguang Lin, Vaughn A Starnes, Ross M Bremner

J Thorac Cardiovasc Surg. 2005 Nov;130(5):1406-12.

PMID: 16256796

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