CAS 110-13-4 2,5-Hexanedione - Analytical Products / Alfa Chemistry

CAT	AP110134
CAS	110-13-4
Structure
MDL Number	MFCD00008792
Molecular Weight	114.14
EC Number	203-738-3
InChI Key	OJVAMHKKJGICOG-UHFFFAOYSA-N
REAXYS Number	506525

Linear Formula

CH3COCH2CH2COCH3

1

2,5-hexanedione Downregulates Nerve Growth Factor and Induces Neuron Apoptosis in the Spinal Cord of Rats via Inhibition of the PI3K/Akt Signaling Pathway

Zhemin Wang, Zewen Qiu, Chenxue Gao, Yijie Sun, Wei Dong, Yan Zhang, Ruolin Chen, Yuan Qi, Shuangyue Li, Yanjie Guo, Yongjun Piao, Sheng Li, Fengyuan Piao

PLoS One. 2017 Jun 27;12(6):e0179388.

PMID: 28654704

1

2,5-Hexanedione Increases the Percentage of Proliferative Sox2

Longjuan Wang, Shuang Liu, Dan Su, Feng Chen, Tengteng Lei, Haibo Chen, Wei Dong, Yue Jiang, Xiance Sun, Wenchang Sun

Toxicol Ind Health. 2018 Sep;34(9):589-595.

PMID: 29764313

1

2,5-hexanedione Induced Apoptosis of Rat Bone Marrow Mesenchymal Stem Cells by Reactive Oxygen Species

Shuang Liu, Feng Chen, Longjuan Wang, Wenchang Sun, Qigui Liu, Haibo Chen, Dan Su, Yue Jiang, Fengyuan Piao, Xiance Sun, Wenfang Sun

J Occup Health. 2016 May 25;58(2):170-8.

PMID: 27010086

1

2,5-Hexanedione Induces Dopaminergic Neurodegeneration Through Integrin α

Cong Zhang, Liyan Hou, Jie Yang, Yuning Che, Fuqiang Sun, Huihua Li, Qingshan Wang

Cell Death Dis. 2018 Jan 19;9(2):60.

PMID: 29352205

1

2,5-hexanedione-induced Testicular Injury

Kim Boekelheide, Shawna L Fleming, Theresa Allio, Michelle E Embree-Ku, Susan J Hall, Kamin J Johnson, Eun Ji Kwon, Sutchin R Patel, Reza J Rasoulpour, Heidi A Schoenfeld, Stephanie Thompson

Annu Rev Pharmacol Toxicol. 2003;43:125-47.

PMID: 12471174

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