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2-Amino-9H-pyrido[2-3-b]indole

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For Research Use Only | Not For Clinical Use
CATAP26148685
CAS26148-68-5
MDL NumberMFCD00210750
Molecular Weight183.21
Description≥98% (HPLC)
SolubilityDMSO: 20 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to light brown
Formpowder
Size5MG, 25MG
Storage Conditions−20°C
1

2-Amino-9H-pyrido[2,3-b]indole (AαC) Adducts and Thiol Oxidation of Serum Albumin as Potential Biomarkers of Tobacco Smoke

Khyatiben V Pathak, Medjda Bellamri, Yi Wang, Sophie Langouët, Robert J Turesky

J Biol Chem. 2015 Jun 26;290(26):16304-18.

PMID: 25953894

1

Bioactivation of the Tobacco Carcinogens 4-aminobiphenyl (4-ABP) and 2-amino-9H-pyrido[2,3-b]indole (AαC) in Human Bladder RT4 Cells

Medjda Bellamri, Lihua Yao, Radha Bonala, Francis Johnson, Linda B Von Weymarn, Robert J Turesky

Arch Toxicol. 2019 Jul;93(7):1893-1902.

PMID: 31203411

1

Effects of 2-amino-9H-pyrido[2,3-b]indole (AαC) Metabolic Bio-Activation on Oxidative DNA Damage in Human Hepatoma G2 (HepG2) Cells

Xianjun Liu, Tingting Zhang, Xiang Li, Ge Zhao, Fuwei Xie

Toxicol Mech Methods. 2018 Mar;28(3):230-237.

PMID: 29022416

1

Metabolism of the Tobacco Carcinogen 2-Amino-9H-pyrido[2,3-b]indole (AαC) in Primary Human Hepatocytes

Medjda Bellamri, Ludovic Le Hegarat, Robert J Turesky, Sophie Langouët

Chem Res Toxicol. 2017 Feb 20;30(2):657-668.

PMID: 27976871

1

UDP-glucuronosyltransferase-mediated Metabolic Activation of the Tobacco Carcinogen 2-amino-9H-pyrido[2,3-b]indole

Yijin Tang, David M LeMaster, Gwendoline Nauwelaërs, Dan Gu, Sophie Langouët, Robert J Turesky

J Biol Chem. 2012 Apr 27;287(18):14960-72.

PMID: 22393056

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