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2-BFI hydrochloride

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For Research Use Only | Not For Clinical Use
CATAP89196952
CAS89196-95-2
Structure
MDL NumberMFCD00672666
Molecular Weight222.67
InChI KeyRFNFFVDVGWOSNZ-UHFFFAOYSA-N
Description≥98% (HPLC)
SolubilityDMSO: 20 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

Antinociceptive Interactions Between the Imidazoline I2 Receptor Agonist 2-BFI and Opioids in Rats: Role of Efficacy at the μ-Opioid Receptor

Justin N Siemian, Samuel Obeng, Yan Zhang, Yanan Zhang, Jun-Xu Li

J Pharmacol Exp Ther. 2016 Jun;357(3):509-19.

PMID: 27056847

1

Chronic Treatment With Selective I2-imidazoline Receptor Ligands Decreases the Content of Pro-Apoptotic Markers in Rat Brain

Celia Garau, Antonio Miralles, Jesús A García-Sevilla

J Psychopharmacol. 2013 Feb;27(2):123-34.

PMID: 22719017

1

Effects of Imidazoline I₂ Receptor Ligands on Morphine- And Tramadol-Induced Antinociception in Rats

David A Thorn, Yanan Zhang, Bi-Wen Peng, Jerrold C Winter, Jun-Xu Li

Eur J Pharmacol. 2011 Nov 30;670(2-3):435-40.

PMID: 21970802

1

Neuroanatomical Characterization of Imidazoline I

Justin N Siemian, Shushan Jia, Jian-Feng Liu, Yanan Zhang, Jun-Xu Li

Eur J Neurosci. 2018 May;47(9):1087-1095.

PMID: 29514408

1

The imidazoline I 2 receptor agonist 2-BFI attenuates hypersensitivity and spinal neuroinflammation in a rat model of neuropathic pain

Justin N Siemian, Zach M LaMacchia, Vilma Spreuer, Jingwei Tian, Tracey A Ignatowski, Pablo M Paez, Yanan Zhang, Jun-Xu Li

Biochem Pharmacol. 2018 Jul;153:260-268.

PMID: 29366977

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