0

2-Hydroxysaclofen

INQUIRY Add to cart
For Research Use Only | Not For Clinical Use
CATAP117354640
CAS117354-64-0
Structure
MDL NumberMFCD00069282
Molecular Weight265.71
InChI KeyWBSMZVIMANOCNX-UHFFFAOYSA-N
Description≥98% (TLC), solid
SolubilityH2O: 1 mg/mL; 0.1 M HCl: 1.2 mg/mL; methanol: 1.4 mg/mL; DMSO: 28 mg/mL; 0.1 M NaOH: 9.5 mg/mL
Assay≥98% (TLC)
Colorwhite
Formsolid
Size2.5MG
1

2-Hydroxysaclofen, a Potent GABAB Receptor Antagonist, Stimulates Luteinizing Hormone Secretion in Female Rats

T Akema, F Kimura

Brain Res. 1991 Apr 12;546(1):143-5.

PMID: 1649666

1

Baclofen and 2-hydroxysaclofen Modify Acute Hypolocomotive and Antinociceptive Effects of Nicotine

Andrés P Varani, Ester Aso, Rafael Maldonado, Graciela N Balerio

Eur J Pharmacol. 2014 Sep 5;738:200-5.

PMID: 24886886

1

Effects of GABAB Receptor Agonists and Antagonists on Glycemia Regulation in Mice

María M Bonaventura, Martín Crivello, María Laura Ferreira, Martín Repetto, Cora Cymeryng, Carlos Libertun, Victoria A Lux-Lantos

Eur J Pharmacol. 2012 Feb 29;677(1-3):188-96.

PMID: 22210053

1

The (S)-enantiomer of 2-hydroxysaclofen Is the Active GABAB Receptor Antagonist in Central and Peripheral Preparations

D I Kerr, J Ong, D J Doolette, K Schafer, R H Prager

Eur J Pharmacol. 1995 Dec 12;287(2):185-9.

PMID: 8749034

1

The GABA-B Antagonist 2-hydroxysaclofen Reverses the Effects of Baclofen on the Discriminative Stimulus Effects of D-amphetamine in the Conditioned Taste Aversion Procedure

Florencio Miranda, Juan C Jiménez, Laura N Cedillo, Alma Sandoval-Sánchez, Patricia Millán-Mejía, Hugo Sánchez-Castillo, David N Velázquez-Martínez

Pharmacol Biochem Behav. 2009 Jul;93(1):25-30.

PMID: 19361543

  • Verification code
Contact Us

Send Us a Request

What is your specific need? We will do everything we can to meet your expectations.
Online Inquiry

Online Inquiry

For any inquiry, question or recommendation, please call: or fill out the following form.

  • Verification code

Head Office

  • Tel:
  • Email:

Follow us on

qrcode