CAS 22753-80-6 2-[N-(2,2,2-Trifluoroethyl)amino]-5-chlorobenzophenone

CAT	AP22753806
CAS	22753-80-6
Structure
Molecular Weight	313.70

Description	United States Pharmacopeia (USP) Reference Standard
Size	25MG

1

(3R)-4-[(3R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-(2,2,2-trifluoroethyl)-1,4-diazepan-2-one, a Selective Dipeptidyl Peptidase IV Inhibitor for the Treatment of Type 2 Diabetes

Tesfaye Biftu, Dennis Feng, Xiaoxia Qian, Gui-Bai Liang, Gerard Kieczykowski, George Eiermann, Huaibing He, Barbara Leiting, Kathy Lyons, Aleksandr Petrov, Ranabir Sinha-Roy, Bei Zhang, Giovanna Scapin, etc.

Bioorg Med Chem Lett. 2007 Jan 1;17(1):49-52.

PMID: 17055272

1

2-Amino-6-arylthio-9-[2-(phosphonomethoxy)ethyl]purine bis(2,2,2-trifluoroethyl) Esters as Novel HBV-specific Antiviral Reagents

Kouichi Sekiya, Hideaki Takashima, Naoko Ueda, Naohiro Kamiya, Satoshi Yuasa, Yoshiyuki Fujimura, Masaru Ubasawa

J Med Chem. 2002 Jul 4;45(14):3138-42.

PMID: 12086499

1

Asymmetric Synthesis of (3S,1'S)-3-(1-amino-2,2,2-trifluoroethyl)-1-(alkyl)-indolin-2-one Derivatives by Addition of (S)-N-t-butylsulfinyl-3,3,3-trifluoroacetaldimine to 1-(alkyl)-indolin-2-ones

Ping Qian, Chen Xie, Lingmin Wu, Haibo Mei, Vadim A Soloshonok, Jianlin Han, Yi Pan

Org Biomol Chem. 2014 Oct 28;12(40):7909-13.

PMID: 25220306

1

Potent, Orally Bioavailable Calcitonin Gene-Related Peptide Receptor Antagonists for the Treatment of Migraine: Discovery of N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1- (2,2,2-trifluoroethyl)azepan-3-yl]-4- (2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin- 1-yl)piperidine-1-carboxamide (MK-0974)

Daniel V Paone, Anthony W Shaw, Diem N Nguyen, Christopher S Burgey, James Z Deng, Stefanie A Kane, Kenneth S Koblan, Christopher A Salvatore, Scott D Mosser, Victor K Johnston, Bradley K Wong, Cynthia M Miller-Stein, etc.

J Med Chem. 2007 Nov 15;50(23):5564-7.

PMID: 17929795

1

Synthesis of 2-amino-6-(4-[11C]methoxyphenylthio)-9-[2-(phosphonomethoxy)ethyl]purine bis(2,2,2-trifluoroethyl) Ester as a Novel Potential PET Gene Reporter Probe for HBV and HSV-tk in Cancers

Ji-Quan Wang, Xiangshu Fei, Thomas A Gardner, Gary D Hutchins, Qi-Huang Zheng

Bioorg Med Chem. 2005 Jan 17;13(2):549-56.

PMID: 15598575

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