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27-hydroxycholesterol

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For Research Use Only | Not For Clinical Use
CATAP20380114
CAS20380-11-4
Structure
Molecular Weight402.65
Description≥98% (HPLC)
SolubilityDMSO: 2 mg/mL, clear (warmed)
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions−20°C
1

27-Hydroxycholesterol Impairs Neuronal Glucose Uptake Through an IRAP/GLUT4 System Dysregulation

Muhammad-Al-Mustafa Ismail, Laura Mateos, Silvia Maioli, Paula Merino-Serrais, Zeina Ali, Maria Lodeiro, Eric Westman, Eran Leitersdorf, Balázs Gulyás, Lars Olof-Wahlund, Bengt Winblad, Irina Savitcheva, etc.

J Exp Med. 2017 Mar 6;214(3):699-717.

PMID: 28213512

1

27-Hydroxycholesterol Links Hypercholesterolemia and Breast Cancer Pathophysiology

Erik R Nelson, Suzanne E Wardell, Jeff S Jasper, Sunghee Park, Sunil Suchindran, Matthew K Howe, Nicole J Carver, Ruchita V Pillai, Patrick M Sullivan, Varun Sondhi, Michihisa Umetani, Joseph Geradts, Donald P McDonnell

Science. 2013 Nov 29;342(6162):1094-8.

PMID: 24288332

1

27-Hydroxycholesterol, an Endogenous Selective Estrogen Receptor Modulator

Sisi He, Erik R Nelson

Maturitas. 2017 Oct;104:29-35.

PMID: 28923174

1

Cholesterol, 24-Hydroxycholesterol, and 27-Hydroxycholesterol as Surrogate Biomarkers in Cerebrospinal Fluid in Mild Cognitive Impairment and Alzheimer's Disease: A Meta-Analysis

Hua-Long Wang, Yan-Yong Wang, Xin-Gang Liu, Sheng-Han Kuo, Na Liu, Qiao-Yun Song, Ming-Wei Wang

J Alzheimers Dis. 2016;51(1):45-55.

PMID: 26836015

1

The Cholesterol Metabolite 27 Hydroxycholesterol Facilitates Breast Cancer Metastasis Through Its Actions on Immune Cells

Amy E Baek, Yen-Rei A Yu, Sisi He, Suzanne E Wardell, Ching-Yi Chang, Sanghoon Kwon, Ruchita V Pillai, Hannah B McDowell, J Will Thompson, Laura G Dubois, Patrick M Sullivan, Jongsook K Kemper, Michael D Gunn, etc.

Nat Commun. 2017 Oct 11;8(1):864.

PMID: 29021522

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