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3α,21-Dihydroxy-5α-pregnan-20-one

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For Research Use Only | Not For Clinical Use
CATAP567022
CAS567-02-2
Structure
MDL NumberMFCD00051144
Molecular Weight334.49
EC Number209-300-8
InChI KeyCYKYBWRSLLXBOW-GDYGHMJCSA-N
Description≥95%
Assay≥95%
Size5MG, 10MG
1

Characterization of Neurosteroid Effects on Hyperpolarizing Current at α4β2δ GABAA Receptors

Qi Hua Gong, Sheryl S Smith

Psychopharmacology (Berl). 2014 Sep;231(17):3525-35.

PMID: 24740493

1

Effect of the Allopregnanolone and Allotetrahydrodeoxycorticosteron on Spike-Wave Discharges in the EEG of Absence Epilepsy Rat Models

Sebahattin Karabulut, Ruslan Bayramov, Keziban Korkmaz Bayramov, Ahmet K Filiz, Ahmet S Taskiran, Ercan Ozdemir

Gen Physiol Biophys. 2018 Mar;37(2):205-211.

PMID: 29593126

1

Mechanism of Potentiation of a Dysfunctional Epilepsy-Linked Mutated GABA(A) Receptor by a Neurosteroid (3alpha, 21-dihydroxy-5alpha-pregnan-20-one): Transient Kinetic Investigations

Latha Ramakrishnan, George P Hess

Biochemistry. 2010 Sep 14;49(36):7892-901.

PMID: 20726514

1

Partial Agonism by 3alpha,21-dihydroxy-5beta-pregnan-20-one at the Gamma-Aminobutyric acidA Receptor Neurosteroid Site

B G Xue, E R Whittemore, C H Park, R M Woodward, N C Lan, K W Gee

J Pharmacol Exp Ther. 1997 Jun;281(3):1095-101.

PMID: 9190841

1

The Influence of Stress at Puberty on Mood and Learning: Role of the α4βδ GABAA Receptor

S S Smith

Neuroscience. 2013 Sep 26;249:192-213.

PMID: 23079628

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