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3-Isobutyl-1-methylxanthine - CAS 28822-58-4

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For Research Use Only | Not For Clinical Use
CATAP28822584
CAS28822-58-4
Structure
Molecular Weight222.24
DescriptionA cell-permeable, non-specific inhibitor of cAMP and cGMP phosphodiesterases (IC₅₀ = 2-50 µM).
Solubilityethanol: 10 mg/mL; DMSO: 100 mM; methanol: 50 mg/mL
Assay≥98% (HPLC)
Colorwhite
Formsolid
Size250MG, 1GM
Storage Conditions-20C
1

Effects of the New Phosphodiesterase Inhibitor Griseolic Acid on Insulin Release in Rat Pancreatic Islets

N Hashimoto, H Makino, A Kanatsuka, M Yamazaki, S Yoshida

Arzneimittelforschung. 1990 Oct;40(10):1098-101.

PMID: 1705426

1

Effects of the Triazolopyrimidine Trapidil on Force of Contraction, Beating Frequency and Phosphodiesterase I--IV Activity in Guinea-Pig Hearts

T Bethke, H Mehl, W Meyer, W Schmitz, H Scholz, K Thomas, H Wenzlaff

Arzneimittelforschung. 1991 May;41(5):461-8.

PMID: 1716891

1

Phosphodiesterase Inhibition by Enoximone in Preparations From Nonfailing and Failing Human Hearts

T Bethke, T Eschenhagen, A Klimkiewicz, C Kohl, H von der Leyen, H Mehl, U Mende, W Meyer, J Neumann, S Rosswag

Arzneimittelforschung. 1992 Apr;42(4):437-45.

PMID: 1386515

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