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3-Pyridyl isothiocyanate

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For Research Use Only | Not For Clinical Use
CATAP17452276
CAS17452-27-6
Structure
MDL NumberMFCD00052351
Molecular Weight136.17
InChI KeyVMSZFBSYWXMXRF-UHFFFAOYSA-N
Description98%
Density1.22 g/mL at 25 °C (lit.)
Assay98%
BP231-233 °C (lit.)
Refractive Indexn20/D 1.665 (lit.)
Size1G, 5G
1

Complete Inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced Rat Lung Tumorigenesis and Favorable Modification of Biomarkers by Phenethyl Isothiocyanate

S S Hecht, N Trushin, J Rigotty, S G Carmella, A Borukhova, S Akerkar, A Rivenson

Cancer Epidemiol Biomarkers Prev. 1996 Aug;5(8):645-52.

PMID: 8824368

1

Effect of Phenethyl Isothiocyanate on the Metabolism of the Tobacco-Specific Nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by Cultured Rat Lung Tissue

K Doerr-O'Rourke, N Trushin, S S Hecht, G D Stoner

Carcinogenesis. 1991 Jun;12(6):1029-34.

PMID: 2044181

1

Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) by Human Cytochrome P450 1A2 and Its Inhibition by Phenethyl Isothiocyanate

T J Smith, Z Guo, F P Guengerich, C S Yang

Carcinogenesis. 1996 Apr;17(4):809-13.

PMID: 8625495

1

Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in Mouse Lung Microsomes and Its Inhibition by Isothiocyanates

T J Smith, Z Y Guo, P E Thomas, F L Chung, M A Morse, K Elkind, C S Yang

Cancer Res. 1990 Nov 1;50(21):6817-22.

PMID: 2208146

1

Synthesis of 5-phenyl-1-(3-pyridyl)-1H-1,2,4-triazole-3-carboxylic Acid Derivatives of Potential Anti-Inflammatory Activity

Safwat M Rabea, Nawal A El-Koussi, Hoda Y Hassan, Tarek Aboul-Fadl

Arch Pharm (Weinheim). 2006 Jan;339(1):32-40.

PMID: 16411174

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