4-1BBL human - Analytical Products / Alfa Chemistry

CAT

IAR4248874

Description	recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture
Assay	≥98% (HPLC); ≥98% (SDS-PAGE)
Color	white to off-white
Form	lyophilized
Impurity Content	<0.1 EU/μg endotoxin, tested
Size	20μG
Storage Conditions	−20°C

1

[Suppression of Tumor Growth Induced by Human 4-1BBL-B7-H3 Gene in Reconstructed Immune Function in Severe Combined Immunodeficient Mice]

Lamei Wu, Hongyu Yang, Juan Luo, Mingyang Su

Hua Xi Kou Qiang Yi Xue Za Zhi. 2014 Apr;32(2):190-5.

PMID: 24881218

1

Crystal Structure of the Human 4-1BB/4-1BBL Complex

Ryan N Gilbreth, Vaheh Y Oganesyan, Hamza Amdouni, Shabazz Novarra, Luba Grinberg, Arnita Barnes, Manuel Baca

J Biol Chem. 2018 Jun 22;293(25):9880-9891.

PMID: 29720399

1

Production of Recombinant Human Trimeric CD137L (4-1BBL). Cross-linking Is Essential to Its T Cell Co-Stimulation Activity

Catherine Rabu, Agnès Quéméner, Yannick Jacques, Klara Echasserieau, Patricia Vusio, François Lang

J Biol Chem. 2005 Dec 16;280(50):41472-81.

PMID: 16204238

1

Structure of the 4-1BB/4-1BBL Complex and Distinct Binding and Functional Properties of Utomilumab and Urelumab

S Michael Chin, Christopher R Kimberlin, Zygy Roe-Zurz, Pamela Zhang, Allison Xu, Sindy Liao-Chan, Debasish Sen, Andrew R Nager, Nicole Schirle Oakdale, Colleen Brown, Feng Wang, Yuting Yang, Kevin Lindquist, etc.

Nat Commun. 2018 Nov 8;9(1):4679.

PMID: 30410017

1

Tumor-targeted 4-1BB Agonists for Combination With T Cell Bispecific Antibodies as Off-The-Shelf Therapy

Christina Claus, Claudia Ferrara, Wei Xu, Johannes Sam, Sabine Lang, Franziska Uhlenbrock, Rosmarie Albrecht, Sylvia Herter, Ramona Schlenker, Tamara Hüsser, Sarah Diggelmann, John Challier, Ekkehard Mössner, etc.

Sci Transl Med. 2019 Jun 12;11(496):eaav5989.

PMID: 31189721

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