CAS 161468-32-2 4-Cyano-3-methylisoquinoline - Analytical Products / Alfa Chemistry

CAT	AP161468322
CAS	161468-32-2
Molecular Weight	168.19

Description	A potent, cell-permeable, reversible, and specific inhibitor of protein kinase A (IC₅₀ = 30 nM).
Solubility	DMSO: 50 mg/mL
Assay	≥95% (HPLC)
Color	white
Form	solid
Size	5MG
Storage Conditions	+2C to +8C

1

A 4-cyano-3-methylisoquinoline Inhibitor of Plasmodium Falciparum Growth Targets the Sodium Efflux Pump PfATP4

Paul R Gilson, Rasika Kumarasingha, Jennifer Thompson, Xinxin Zhang, Jocelyn Sietsma Penington, Robabeh Kalhor, Hayley E Bullen, Adele M Lehane, Madeline G Dans, Tania F de Koning-Ward, Jessica K Holien, etc.

Sci Rep. 2019 Jul 16;9(1):10292.

PMID: 31311978

1

Antimalarial Activity of Novel 4-cyano-3-methylisoquinoline Inhibitors Against Plasmodium Falciparum: Design, Synthesis and Biological Evaluation

Melissa J Buskes, Katherine L Harvey, Benjamin J Richards, Robabeh Kalhor, Rebecca M Christoff, Chamodi K Gardhi, Dene R Littler, Elliott D Cope, Boris Prinz, Greta E Weiss, Nathan J O'Brien, Brendan S Crabb, etc.

Org Biomol Chem. 2016 May 18;14(20):4617-39.

PMID: 27105169

1

Involvement of Cyclic AMP-mediated Pathway in Neural Release of Noradrenaline in Canine Isolated Mesenteric Artery and Vein

Violeta N Mutafova-Yambolieva, Lisa Smyth, Janette Bobalova

Cardiovasc Res. 2003 Jan;57(1):217-24.

PMID: 12504831

1

Multiple Signalling Pathways Involved in beta2-adrenoceptor-mediated Glucose Uptake in Rat Skeletal Muscle Cells

Julia Nevzorova, Bronwyn A Evans, Tore Bengtsson, Roger J Summers

Br J Pharmacol. 2006 Feb;147(4):446-54.

PMID: 16415914

1

The Expression of a High Level of Morphine Antinociceptive Tolerance in Mice Involves Both PKC and PKA

Forrest L Smith, Ruby R Javed, Mark J Elzey, William L Dewey

Brain Res. 2003 Sep 19;985(1):78-88.

PMID: 12957370

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