CAS 1952-15-4 4-DAMP - Analytical Products / Alfa Chemistry

CAT	AP1952154
CAS	1952-15-4
Structure
MDL Number	MFCD00078564
Molecular Weight	451.34
InChI Key	WWJHRSCUAQPFQO-UHFFFAOYSA-M

Description	≥98% (HPLC)
Solubility	DMSO: ≥15 mg/mL
Assay	≥98% (HPLC)
Color	white to beige
Form	powder
Size	10MG, 50MG
Storage Conditions	room temp

1

Conversion of N-(2-chloroethyl)-4-piperidinyl Diphenylacetate (4-DAMP Mustard) to an Aziridinium Ion and Its Interaction With Muscarinic Receptors in Various Tissues

E A Thomas, H H Hsu, M T Griffin, A L Hunter, T Luong, F J Ehlert

Mol Pharmacol. 1992 Apr;41(4):718-26.

PMID: 1569923

1

Loss of [3H]4-DAMP Binding to Muscarinic Receptors in the Orbitofrontal Cortex of Alzheimer's Disease Patients With Psychosis

S W Y Tsang, P T Francis, M M Esiri, P T H Wong, C P L H Chen, M K P Lai

Psychopharmacology (Berl). 2008 Jun;198(2):251-9.

PMID: 18373228

1

Regional Binding of 4-diphenylacetoxy-N-methylpiperidine Methobromide (4-DAMP) to Muscarinic Receptors in Rat Brain and Comparative Analysis of Minimum Energy Conformations

D Collins, D A Smith, W S Messer Jr

Neurochem Int. 1993 Mar;22(3):237-47.

PMID: 8443567

1

The Interaction of 4-DAMP Mustard With Subtypes of the Muscarinic Receptor

F J Ehlert

Life Sci. 1996;58(22):1971-8.

PMID: 8637426

1

The Use of a Modified [3H]4-DAMP Radioligand Binding Assay With Increased Selectivity for Muscarinic M3 Receptor Shows That Cortical CHRM3 Levels Are Not Altered in Mood Disorders

Won Je Jeon, Andrew S Gibbons, Brian Dean

Prog Neuropsychopharmacol Biol Psychiatry. 2013 Dec 2;47:7-12.

PMID: 23962466

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