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4′-Hydroxydiclofenac

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For Research Use Only | Not For Clinical Use
CATAP64118849-B
CAS64118-84-9
Structure
MDL NumberMFCD01671980
Molecular Weight312.15
InChI KeyKGVXVPRLBMWZLG-UHFFFAOYSA-N
REAXYS Number4198042
Descriptionanalytical standard
Formneat; gas chromatography (GC): suitable
Gradeanalytical standard
Size10MG
Storage Conditions2-8°C
1

Efficient High Performance Liquid chromatograph/ultraviolet Method for Determination of Diclofenac and 4'-hydroxydiclofenac in Rat Serum

Lata Kaphalia, Bhupendra S Kaphalia, Santosh Kumar, Mary F Kanz, Mary Treinen-Moslen

J Chromatogr B Analyt Technol Biomed Life Sci. 2006 Jan 18;830(2):231-7.

PMID: 16301007

1

Elucidation of Biotransformation of Diclofenac and 4'hydroxydiclofenac During Biological Wastewater Treatment

Helene Bouju, Peter Nastold, Birgit Beck, Juliane Hollender, Philippe F-X Corvini, Thomas Wintgens

J Hazard Mater. 2016 Jan 15;301:443-52.

PMID: 26410273

1

Endocrine Disrupting Activities and Immunomodulatory Effects in Lymphoblastoid Cell Lines of Diclofenac, 4-hydroxydiclofenac and Paracetamol

Ivana Klopčič, Tijana Markovič, Irena Mlinarič-Raščan, Marija Sollner Dolenc

Toxicol Lett. 2018 Sep 15;294:95-104.

PMID: 29777833

1

In Vivo and in Vitro Diclofenac 5-hydroxylation Mediated Primarily by Cytochrome P450 3A Enzymes in Common Marmoset Livers Genotyped for P450 2C19 Variants

Kazuyuki Nakanishi, Shotaro Uehara, Takashi Kusama, Takashi Inoue, Kanami Shimura, Yusuke Kamiya, Norie Murayama, Makiko Shimizu, Yasuhiro Uno, Erika Sasaki, Hiroshi Yamazaki

Biochem Pharmacol. 2018 Jun;152:272-278.

PMID: 29626440

1

Metabolic Activation of Diclofenac by Human Cytochrome P450 3A4: Role of 5-hydroxydiclofenac

S Shen, M R Marchick, M R Davis, G A Doss, L R Pohl

Chem Res Toxicol. 1999 Feb;12(2):214-22.

PMID: 10027801

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