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4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) solution

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For Research Use Only | Not For Clinical Use
CATAP64091914-A
CAS64091-91-4
Structure
MDL NumberMFCD00274580
Molecular Weight207.23
InChI KeyFLAQQSHRLBFIEZ-UHFFFAOYSA-N
Description1.0 mg/mL in methanol, ampule of 1 mL, certified reference material
Gradecertified reference material
Size1ML
Storage Conditions−20°C
1

Development, Validation, and Application of a Liquid Chromatography-Tandem Mass Spectrometry Method for the Determination of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in Human Hair

Li Yao, Jun Yang, Ya-feng Guan, Bai-zhan Liu, Sai-jing Zheng, Wei-miao Wang, Xiao-lan Zhu, Zhi-dan Zhang

Anal Bioanal Chem. 2012 Nov;404(8):2259-66.

PMID: 22926132

1

Effect of Snuff and Nicotine on DNA Methylation by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone

G Prokopczyk, J D Adams, E J LaVoie, D Hoffmann

Carcinogenesis. 1987 Oct;8(10):1395-7.

PMID: 3652377

1

Formamidopyrimidine Adducts Are Detected Using the Comet Assay in Human Cells Treated With Reactive Metabolites of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)

Sandrine Lacoste, André Castonguay, Régen Drouin

Mutat Res. 2006 Aug 30;600(1-2):138-49.

PMID: 16914170

1

Inhibition of Adenoma Progression to Adenocarcinoma in a 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced Lung Tumorigenesis Model in A/J Mice by Tea Polyphenols and Caffeine

Gang Lu, Jie Liao, Guangyu Yang, Kenneth R Reuhl, Xingpei Hao, Chung S Yang

Cancer Res. 2006 Dec 1;66(23):11494-501.

PMID: 17145898

1

Permeation and Reservoir Formation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and Benzo[a]pyrene (B[a]P) Across Porcine Esophageal Tissue in the Presence of Ethanol and Menthol

Chadi Azzi, Jin Zhang, Carryn H Purdon, James M Chapman, Daniela Nitcheva, James R Hebert, Eric W Smith

Carcinogenesis. 2006 Jan;27(1):137-45.

PMID: 16000402

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