CAS 134865-74-0 4-P-PDOT - Analytical Products / Alfa Chemistry

CAT	AP134865740
CAS	134865-74-0
Structure
Molecular Weight	279.38

Description	≥98% (HPLC)
Solubility	DMSO: 5 mg/mL, clear (warmed)
Assay	≥98% (HPLC)
Color	white to beige
Form	powder
Size	5MG, 25MG
Storage Conditions	room temp

1

An Improved Synthesis of cis-4-phenyl-2-propionamidotetralin (4-P-PDOT): A Selective MT(2) Melatonin Receptor Antagonist

Simone Lucarini, Annalida Bedini, Gilberto Spadoni, Giovanni Piersanti

Org Biomol Chem. 2008 Jan 7;6(1):147-50.

PMID: 18075659

1

Copper chelators promote nonamyloidogenic processing of AβPP via MT 1/2 /CREB-dependent signaling pathways in AβPP/PS1 transgenic mice

Zhuo Wang, Ya-Hong Zhang, Wei Zhang, Hui-Ling Gao, Man-Li Zhong, Ting-Ting Huang, Rui-Fang Guo, Na-Na Liu, Dan-Dan Li, Yin Li, Zhan-You Wang, Pu Zhao

J Pineal Res. 2018 Oct;65(3):e12502.

PMID: 29710396

1

Stimulatory Effects of Melatonin on Porcine In Vitro Maturation Are Mediated by MT2 Receptor

Sanghoon Lee, Jun-Xue Jin, Anukul Taweechaipaisankul, Geon-A Kim, Byeong-Chun Lee

Int J Mol Sci. 2018 May 26;19(6):1581.

PMID: 29861447

1

The Influence Od Melatonin Receptors Antagonists, Luzindole and 4-phenyl-2-propionamidotetralin (4-P-PDOT), on Melatonin-Dependent Vasopressin and Adrenocorticotropic Hormone (ACTH) Release From the Rat Hypothalamo-Hypophysial System. In Vitro and in Vivo Studies

M Juszczak, M Roszczyk, E Kowalczyk, B Stempniak

J Physiol Pharmacol. 2014 Dec;65(6):777-84.

PMID: 25554981

1

Toward the Definition of Stereochemical Requirements for MT2-selective Antagonists and Partial Agonists by Studying 4-phenyl-2-propionamidotetralin Derivatives

Annalida Bedini, Simone Lucarini, Gilberto Spadoni, Giorgio Tarzia, Francesco Scaglione, Silvana Dugnani, Marilou Pannacci, Valeria Lucini, Caterina Carmi, Daniele Pala, Silvia Rivara, Marco Mor

J Med Chem. 2011 Dec 22;54(24):8362-72.

PMID: 22047556

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