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6,7-Dihydroxycoumarin

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For Research Use Only | Not For Clinical Use
CATAP305011
CAS305-01-1
Structure
MDL NumberMFCD00006874
Molecular Weight178.14
EC Number206-161-5
InChI KeyILEDWLMCKZNDJK-UHFFFAOYSA-N
REAXYS Number152788
Description98%
Assay98%
MP271-273 °C (lit.)
Size1G, 5G
1

[6.7-Dihydroxycoumarin (Aesculetin) as a Substrate for Catechol-O-Methyltransferase (Author's Transl)]

D Müller-Enoch, E Seidl, H Thomas

Z Naturforsch C Biosci. May-Jun 1976;31(5-6):280-4.

PMID: 134569

1

Aesculetin (6,7-dihydroxycoumarin) Exhibits Potent and Selective Antitumor Activity in Human Acute Myeloid Leukemia Cells (THP-1) via Induction of Mitochondrial Mediated Apoptosis and Cancer Cell Migration Inhibition

Jian Gong, Wei-Guo Zhang, Xiao-Fen Feng, Mei-Juan Shao, Chao Xing

J BUON. Nov-Dec 2017;22(6):1563-1569.

PMID: 29332353

1

Effects of Esculetin (6,7-dihydroxycoumarin) on Guinea-Pig Tracheal Chains in Vitro

E Ragazzi, G Froldi, G Fassina

Pharmacol Res. Mar-Apr 1989;21(2):183-92.

PMID: 2501776

1

Esculetin (6,7-dihydroxycoumarin): A Potential Cancer Chemopreventive Agent Through Suppression of Sp1 in Oral Squamous Cancer Cells

Jin Hyoung Cho, Jae-Cheon Shin, Jung-Jae Cho, Yung Hyun Choi, Jung-Hyun Shim, Jung-Il Chae

Int J Oncol. 2015 Jan;46(1):265-71.

PMID: 25310400

1

Immunomodulatory Effects of Esculetin (6,7-dihydroxycoumarin) on Murine Lymphocytes and Peritoneal Macrophages

Kwok-nam Leung, Pui-yin Leung, Lai-ping Kong, Po-ki Leung

Cell Mol Immunol. 2005 Jun;2(3):181-8.

PMID: 16212885

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