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6-Aminophenanthridine

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For Research Use Only | Not For Clinical Use
CATAP832688
CAS832-68-8
Structure
Molecular Weight194.23
Description≥98% (HPLC)
SolubilityDMSO: 20 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to brown
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

Antiprion Drugs 6-aminophenanthridine and Guanabenz Reduce PABPN1 Toxicity and Aggregation in Oculopharyngeal Muscular Dystrophy

Nicolas Barbezier, Aymeric Chartier, Yannick Bidet, Anja Buttstedt, Cécile Voisset, Hervé Galons, Marc Blondel, Elisabeth Schwarz, Martine Simonelig

EMBO Mol Med. 2011 Jan;3(1):35-49.

PMID: 21204267

1

Evaluation of the Antiprion Activity of 6-aminophenanthridines and Related Heterocycles

Phuhai Nguyen, Nassima Oumata, Flavie Soubigou, Justine Evrard, Nathalie Desban, Pascale Lemoine, Serge Bouaziz, Marc Blondel, Cécile Voisset

Eur J Med Chem. 2014 Jul 23;82:363-71.

PMID: 24927056

1

Spectroscopic and DFT Studies on 6-aminophenanthridine and Its Derivatives Provide Insights in Their Activity Towards Ribosomal RNA

Debapriya Banerjee, Hakkim Vovusha, Yanhong Pang, Nassima Oumata, Biplab Sanyal, Suparna Sanyal

Biochimie. 2014 Feb;97:194-9.

PMID: 24184272

1

Synthesis of Conjugates of 6-aminophenanthridine and Guanabenz, Two Structurally Unrelated Prion Inhibitors, for the Determination of Their Cellular Targets by Affinity Chromatography

Fabienne Gug, Nassima Oumata, Déborah Tribouillard-Tanvier, Cécile Voisset, Nathalie Desban, Stéphane Bach, Marc Blondel, Hervé Galons

Bioconjug Chem. 2010 Feb 17;21(2):279-88.

PMID: 20092293

1

The Antiprion Compound 6-aminophenanthridine Inhibits the Protein Folding Activity of the Ribosome by Direct Competition

Yanhong Pang, Sriram Kurella, Cécile Voisset, Dibyendu Samanta, Debapriya Banerjee, Ariane Schabe, Chanchal Das Gupta, Hervé Galons, Marc Blondel, Suparna Sanyal

J Biol Chem. 2013 Jun 28;288(26):19081-9.

PMID: 23673663

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