7-Ethoxy-4-(trifluoromethyl)coumarin

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For Research Use Only | Not For Clinical Use

CAT	AP115453822
CAS	115453-82-2
Structure
MDL Number	MFCD00467588
Molecular Weight	258.19
InChI Key	OLHOIERZAZMHGK-UHFFFAOYSA-N
REAXYS Number	8555209

Description	≥98% (TLC)
Assay	≥98% (TLC)
Size	5MG
Storage Conditions	−20°C

Coumarin Derivatives as Substrate Probes of Mammalian Cytochromes P450 2B4 and 2B6: Assessing the Importance of 7-Alkoxy Chain Length, Halogen Substitution, and Non-Active Site Mutations

Jingbao Liu, Manish B Shah, Qinghai Zhang, C David Stout, James R Halpert, P Ross Wilderman

Biochemistry. 2016 Apr 5;55(13):1997-2007.

PMID: 26982502

Mechanistic Studies With N-benzyl-1-aminobenzotriazole-inactivated CYP2B1: Differential Effects on the Metabolism of 7-ethoxy-4-(trifluoromethyl)coumarin, Testosterone, and Benzphetamine

Ute M Kent, Lise Pascual, Rebecca A Roof, David P Ballou, Paul F Hollenberg

Arch Biochem Biophys. 2004 Mar 15;423(2):277-87.

PMID: 15001392

Rational Re-Engineering of the O-Dealkylation of 7-Alkoxycoumarin Derivatives by Cytochromes P450 2B From the Desert Woodrat Neotoma Lepida

Lu Huo, Jingbao Liu, M Denise Dearing, Grazyna D Szklarz, James R Halpert, P Ross Wilderman

Biochemistry. 2017 Apr 25;56(16):2238-2246.

PMID: 28375626

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