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7-Ethyl-10-hydroxycamptothecin

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For Research Use Only | Not For Clinical Use
CATAP86639523-B
CAS86639-52-3
MDL NumberMFCD00871873
Molecular Weight392.40
InChI KeyFJHBVJOVLFPMQE-QFIPXVFZSA-N
Description≥98% (HPLC), powder
SolubilityDMSO: 1 mg/mL
Assay≥98% (HPLC)
Formpowder
Size10MG, 50MG
Storage Conditions−20°C
1

Advances in Delivery of Irinotecan (CPT-11) Active Metabolite 7-ethyl-10-hydroxycamptothecin

Jingxing Si, Xiaobao Zhao, Shan Gao, Dongsheng Huang, Meihua Sui

Int J Pharm. 2019 Sep 10;568:118499.

PMID: 31299338

1

Antibody-drug Conjugates of 7-ethyl-10-hydroxycamptothecin: Sacituzumab Govitecan and Labetuzumab Govitecan

Wenjuan Dong, Jianyou Shi, Ting Yuan, Baowen Qi, Jiying Yu, Jingying Dai, Lin He

Eur J Med Chem. 2019 Apr 1;167:583-593.

PMID: 30822636

1

Co-Prodrugs of 7-Ethyl-10-hydroxycamptothecin and Vorinostat With in Vitro Hydrolysis and Anticancer Effects

Shuangxi Liu, Zonglong Hu, Qiumeng Zhang, Qiwen Zhu, Yi Chen, Wei Lu

ACS Omega. 2019 Dec 23;5(1):350-357.

PMID: 31956782

1

Dual 7-ethyl-10-hydroxycamptothecin Conjugated Phospholipid Prodrug Assembled Liposomes With in Vitro Anticancer Effects

Yawei Du, Wei Zhang, Ruiyu He, Muhammad Ismail, Longbing Ling, Chen Yao, Zhenglin Fu, Xinsong Li

Bioorg Med Chem. 2017 Jun 15;25(12):3247-3258.

PMID: 28465086

1

Excipient-free Nanodispersion of 7-ethyl-10-hydroxycamptothecin Exerts Potent Therapeutic Effects Against Pancreatic Cancer Cell Lines and Patient-Derived Xenografts

Linshi Zhang, Jiarong Zhou, Yingcai Yan, Xiaohu Zhou, Quan Zhou, Rong Du, Shiqi Hu, Wenhao Ge, Yu Huang, Hao Xu, Yang Kong, Huilin Zheng, Yuan Ding, Youqing Shen, Weilin Wang

Cancer Lett. 2019 Nov 28;465:36-44.

PMID: 31479691

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