CAS 575-04-2 7-Methoxy-4-(trifluoromethyl)coumarin - Analytical Products / Alfa Chemistry

CAT	AP575042
CAS	575-04-2
MDL Number	MFCD00132980
Molecular Weight	244.17
InChI Key	HAZHUELNIGDYQH-UHFFFAOYSA-N
REAXYS Number	225039

Description	≥99% (TLC)
Assay	≥99% (TLC)
Size	100MG

1

Comparison of in Vitro Activities of Biotransformation Enzymes in Pig, Cattle, Goat and Sheep

B Szotáková, V Baliharová, J Lamka, E Nozinová, V Wsól, J Velík, M Machala, J Neca, P Soucek, S Susová, L Skálová

Res Vet Sci. 2004 Feb;76(1):43-51.

PMID: 14659728

1

Effects of Cytochrome P450 Inhibitors on the Biotransformation of Fluorogenic Substrates by Adult Male Rat Liver Microsomes and cDNA-expressed Rat Cytochrome P450 Isoforms

Emilija Makaji, Cristina S Trambitas, Pamela Shen, Alison C Holloway, Denis J Crankshaw

Toxicol Sci. 2010 Feb;113(2):293-304.

PMID: 19858067

1

Identification and Analysis of Conserved Sequence Motifs in Cytochrome P450 Family 2. Functional and Structural Role of a Motif 187RFDYKD192 in CYP2B Enzymes

Numan Oezguen, Santosh Kumar, Aditya Hindupur, Werner Braun, B K Muralidhara, James R Halpert

J Biol Chem. 2008 Aug 1;283(31):21808-16.

PMID: 18495666

1

Investigation by Site-Directed Mutagenesis of the Role of Cytochrome P450 2B4 Non-Active-Site Residues in Protein-Ligand Interactions Based on Crystal Structures of the Ligand-Bound Enzyme

P Ross Wilderman, Sean C Gay, Hyun-Hee Jang, Qinghai Zhang, C David Stout, James R Halpert

FEBS J. 2012 May;279(9):1607-20.

PMID: 22051155

1

Structure-Function Analysis of Mammalian CYP2B Enzymes Using 7-Substituted Coumarin Derivatives as Probes: Utility of Crystal Structures and Molecular Modeling in Understanding Xenobiotic Metabolism

Manish B Shah, Jingbao Liu, Lu Huo, Qinghai Zhang, M Denise Dearing, P Ross Wilderman, Grazyna D Szklarz, C David Stout, James R Halpert

Mol Pharmacol. 2016 Apr;89(4):435-45.

PMID: 26826176

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