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8-Aminoguanine

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For Research Use Only | Not For Clinical Use
CATAP28128418
CAS28128-41-8
Structure
Molecular Weight166.14
Description≥95% (HPLC)
Solubility0.1 M NaOH: 2 mg/mL, clear (warmed)
Assay≥95% (HPLC)
Colorwhite to beige
Formpowder
Size25MG
Storage Conditions2-8°C
1

8-Aminoguanine Induces Diuresis, Natriuresis, and Glucosuria by Inhibiting Purine Nucleoside Phosphorylase and Reduces Potassium Excretion by Inhibiting Rac1

Edwin K Jackson, Zaichuan Mi, Thomas R Kleyman, Dongmei Cheng

J Am Heart Assoc. 2018 Nov 6;7(21):e010085.

PMID: 30608204

1

8-Aminoguanine: A Base Modification Produced in Rat Liver Nucleic Acids by the Hepatocarcinogen 2-nitropropane

R S Sodum, G Nie, E S Fiala

Chem Res Toxicol. May-Jun 1993;6(3):269-76.

PMID: 8318648

1

8-Aminoguanosine and 8-Aminoguanine Exert Diuretic, Natriuretic, Glucosuric, and Antihypertensive Activity

Edwin K Jackson, Delbert G Gillespie, Zaichuan Mi

J Pharmacol Exp Ther. 2016 Dec;359(3):420-435.

PMID: 27679494

1

8-Aminoguanosine Exerts Diuretic, Natriuretic, and Glucosuric Activity via Conversion to 8-Aminoguanine, Yet Has Direct Antikaliuretic Effects

Edwin K Jackson, Zaichuan Mi

J Pharmacol Exp Ther. 2017 Dec;363(3):358-366.

PMID: 28928119

1

Correction to "8-Aminoguanosine and 8-Aminoguanine Exert Diuretic, Natriuretic, Glucosuric, and Antihypertensive Activity"

J Pharmacol Exp Ther. 2017 Dec;363(3):411.

PMID: 29146684

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