8-Chloroadenosine 3′,5′-cyclic-monophosphate

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For Research Use Only | Not For Clinical Use

CAT	AP41941564
CAS	41941-56-4
Structure
MDL Number	MFCD00153938
Molecular Weight	363.65
InChI Key	CLLFEJLEDNXZNR-UHFFFAOYSA-N

Description	≥85%
Solubility	aqueous base: soluble
Assay	≥85%
Size	5MG, 10MG
Storage Conditions	−20°C

8-Cl-cAMP and PKA I-selective cAMP Analogs Effectively Inhibit Undifferentiated Thyroid Cancer Cell Growth

Elisa Stellaria Grassi, Alessandra Dicitore, Irene Negri, Maria Orietta Borghi, Giovanni Vitale, Luca Persani

Endocrine. 2017 May;56(2):388-398.

PMID: 27460006

Inhibition of the Self-Renewal Capacity of Blast Progenitors From Acute Myeloblastic Leukemia Patients by Site-Selective 8-chloroadenosine 3',5'-cyclic Monophosphate

A Pinto, D Aldinucci, V Gattei, V Zagonel, G Tortora, A Budillon, Y S Cho-Chung

Proc Natl Acad Sci U S A. 1992 Oct 1;89(19):8884-8.

PMID: 1329084

Site-selective 8-chloroadenosine 3',5'-cyclic Monophosphate Inhibits Transformation and Transforming Growth Factor Alpha Production in Ki-ras-transformed Rat Fibroblasts

G Tortora, F Ciardiello, S Ally, T Clair, D S Salomon, Y S Cho-Chung

FEBS Lett. 1989 Jan 2;242(2):363-7.

PMID: 2536620

The cAMP Analogs Have Potent Anti-Proliferative Effects on Medullary Thyroid Cancer Cell Lines

Alessandra Dicitore, Elisa Stellaria Grassi, Michele Caraglia, Maria Orietta Borghi, Germano Gaudenzi, Leo J Hofland, Luca Persani, Giovanni Vitale

Endocrine. 2016 Jan;51(1):101-12.

PMID: 25863490

The Facile and Efficient Synthesis of 8-chloroadenosine 3',5'-cyclic Monophosphate by Phosphorylative Cyclization of 8-chloroadenosine and Its Characterization by(1)H and (13)C NMR Spectroscopy

N T Woo, S Y Jin, D J Cho, N S Kim, E H Bae, J H Jung, W H Ham, Y H Jung

Arch Pharm Res. 1997 Apr;20(2):176-9.

PMID: 18975197

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