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A-484954

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For Research Use Only | Not For Clinical Use
CATAP142557617-A
CAS142557-61-7
Structure
Molecular Weight289.29
Description≥98% (HPLC)
SolubilityDMSO: 3 mg/mL, clear (warmed)
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG
Storage Conditions2-8°C
1

1-Benzyl-3-cetyl-2-methylimidazolium Iodide (NH125) Induces Phosphorylation of Eukaryotic Elongation factor-2 (eEF2): A Cautionary Note on the Anticancer Mechanism of an eEF2 Kinase Inhibitor

Zehan Chen, Sujatha M Gopalakrishnan, Mai-Ha Bui, Niru B Soni, Usha Warrior, Eric F Johnson, Jennifer B Donnelly, Keith B Glaser

J Biol Chem. 2011 Dec 23;286(51):43951-8.

PMID: 22020937

1

Eukaryotic Elongation Factor 2 Kinase Controls Proliferation and Migration of Vascular Smooth Muscle Cells

T Usui, R Nijima, T Sakatsume, K Otani, S Kameshima, M Okada, H Yamawaki

Acta Physiol (Oxf). 2015 Feb;213(2):472-80.

PMID: 25069823

1

Eukaryotic Elongation Factor 2 Kinase Mediates Monocrotaline-Induced Pulmonary Arterial Hypertension via Reactive Oxygen Species-Dependent Vascular Remodeling

Satoshi Kameshima, Kyosuke Kazama, Muneyoshi Okada, Hideyuki Yamawaki

Am J Physiol Heart Circ Physiol. 2015 May 15;308(10):H1298-305.

PMID: 25770246

1

NH125 Reduces the Level of CPEB3, an RNA Binding Protein, to Promote Synaptic GluA2 Expression

Crhistian L Bender, Qian Yang, Lu Sun, Siqiong June Liu

Neuropharmacology. 2016 Feb;101:531-7.

PMID: 25842244

1

Using Docking and Alchemical Free Energy Approach to Determine the Binding Mechanism of eEF2K Inhibitors and Prioritizing the Compound Synthesis

Qiantao Wang, Ramakrishna Edupuganti, Clint D J Tavares, Kevin N Dalby, Pengyu Ren

Front Mol Biosci. 2015 Mar 19;2:9.

PMID: 25988177

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