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A-841720

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For Research Use Only | Not For Clinical Use
CATAP869802584
CAS869802-58-4
Structure
Molecular Weight343.45
Description≥98% (HPLC)
SolubilityDMSO: 15 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

Analgesic Activity of Metabotropic Glutamate Receptor 1 Antagonists on Spontaneous Post-Operative Pain in Rats

Chang Z Zhu, Scott Baker, Odile EI-Kouhen, Sonya G Lehto, Peter R Hollingsworth, Donna M Gauvin, Gricelda Hernandez, GuoZhu Zheng, Renjie Chang, Robert B Moreland, Andrew O Stewart, Jorge D Brioni, Prisca Honore

Eur J Pharmacol. 2008 Feb 12;580(3):314-21.

PMID: 18054908

1

Blockade of mGluR1 Receptor Results in Analgesia and Disruption of Motor and Cognitive Performances: Effects of A-841720, a Novel Non-Competitive mGluR1 Receptor Antagonist

O El-Kouhen, S G Lehto, J B Pan, R Chang, S J Baker, C Zhong, P R Hollingsworth, J P Mikusa, E A Cronin, K L Chu, S P McGaraughty, M E Uchic, L N Miller, N M Rodell, M Patel, P Bhatia, M Mezler, T Kolasa, etc.

Br J Pharmacol. 2006 Nov;149(6):761-74.

PMID: 17016515

1

Comparison of the mGluR1 Antagonist A-841720 in Rat Models of Pain and Cognition

Lorenzo Morè, Andreas Gravius, Malgorzata Pietraszek, Irina Belozertseva, Andrey Malyshkin, Elena Shekunova, Caroline Barberi, Daniela Schaefer, Werner J Schmidt, Wojciech Danysz

Behav Pharmacol. 2007 Jul;18(4):273-81.

PMID: 17551319

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