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A12B4C3

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For Research Use Only | Not For Clinical Use
CATAP1005129805
CAS1005129-80-5
MDL NumberMFCD17215976
Molecular Weight534.65
InChI KeyKVHGJAKTBPFFNV-UHFFFAOYSA-N
Description≥98% (HPLC)
SolubilityDMSO: ≥20 mg/mL
Assay≥98% (HPLC)
Coloryellow
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

Identification of a Small Molecule Inhibitor of the Human DNA Repair Enzyme Polynucleotide kinase/phosphatase

Gary K Freschauf, Feridoun Karimi-Busheri, Agnieszka Ulaczyk-Lesanko, Todd R Mereniuk, Ashley Ahrens, Jonathan M Koshy, Aghdass Rasouli-Nia, Phuwadet Pasarj, Charles F B Holmes, Frauke Rininsland, Dennis G Hall, etc.

Cancer Res. 2009 Oct 1;69(19):7739-46.

PMID: 19773431

1

Mechanism of Action of an Imidopiperidine Inhibitor of Human Polynucleotide kinase/phosphatase

Gary K Freschauf, Rajam S Mani, Todd R Mereniuk, Mesfin Fanta, Caesar A Virgen, Grigory L Dianov, Jean-Marie Grassot, Dennis G Hall, Michael Weinfeld

J Biol Chem. 2010 Jan 22;285(4):2351-60.

PMID: 19940137

1

Multicomponent Hetero-[4 + 2] Cycloaddition/Allylboration Reaction: From Natural Product Synthesis to Drug Discovery

Dennis G Hall, Taras Rybak, Tristan Verdelet

Acc Chem Res. 2016 Nov 15;49(11):2489-2500.

PMID: 27753496

1

The Human Polynucleotide kinase/phosphatase (hPNKP) Inhibitor A12B4C3 Radiosensitizes Human Myeloid Leukemia Cells to Auger Electron-Emitting anti-CD123 ¹¹¹In-NLS-7G3 Radioimmunoconjugates

Arman Zereshkian, Jeffrey V Leyton, Zhongli Cai, Dane Bergstrom, Michael Weinfeld, Raymond M Reilly

Nucl Med Biol. May-Jun 2014;41(5):377-83.

PMID: 24637100

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