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A20 human

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For Research Use Only | Not For Clinical Use
CATIAR42413759
Descriptionrecombinant, expressed in baculovirus infected Sf9 cells, ≥20% (SDS-PAGE)
Assay≥20% (SDS-PAGE)
Formaqueous solution
Size50μG
Storage Conditions−70°C
1

A20 Prevents Inflammasome-Dependent Arthritis by Inhibiting Macrophage Necroptosis Through Its ZnF7 Ubiquitin-Binding Domain

Apostolos Polykratis, Arne Martens, Remzi Onur Eren, Yoshitaka Shirasaki, Mai Yamagishi, Yoshifumi Yamaguchi, Sotaro Uemura, Masayuki Miura, Bernhard Holzmann, George Kollias, Marietta Armaka, Geert van Loo, etc.

Nat Cell Biol. 2019 Jun;21(6):731-742.

PMID: 31086261

1

A20: A Multifunctional Tool for Regulating Immunity and Preventing Disease

Barbara A Malynn, Averil Ma

Cell Immunol. 2019 Jun;340:103914.

PMID: 31030956

1

A20: Linking a Complex Regulator of Ubiquitylation to Immunity and Human Disease

Averil Ma, Barbara A Malynn

Nat Rev Immunol. 2012 Nov;12(11):774-85.

PMID: 23059429

1

Denisovan, Modern Human and Mouse TNFAIP3 Alleles Tune A20 Phosphorylation and Immunity

Nathan W Zammit, Owen M Siggs, Paul E Gray, Keisuke Horikawa, David B Langley, Stacey N Walters, Stephen R Daley, Claudia Loetsch, Joanna Warren, Jin Yan Yap, Daniele Cultrone, Amanda Russell, Elisabeth K Malle, etc.

Nat Immunol. 2019 Oct;20(10):1299-1310.

PMID: 31534238

1

The Ubiquitin-Modifying Enzyme A20 Restricts Ubiquitination of the Kinase RIPK3 and Protects Cells From Necroptosis

Michio Onizawa, Shigeru Oshima, Ulf Schulze-Topphoff, Juan A Oses-Prieto, Timothy Lu, Rita Tavares, Thomas Prodhomme, Bao Duong, Michael I Whang, Rommel Advincula, Alex Agelidis, Julio Barrera, Hao Wu, etc.

Nat Immunol. 2015 Jun;16(6):618-27.

PMID: 25939025

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