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Adenosine A 2A/A₁ Receptor Antagonist

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For Research Use Only | Not For Clinical Use
CATIAR4249383
Molecular Weight402.45
DescriptionThe Adenosine A2A/A₁ Receptor Antagonist controls the biological activity of Adenosine A2A/A₁ Receptor. This small molecule/inhibitor is primarily used for Biochemicals applications.
SolubilityDMSO: 10 mg/mL, clear, yellow
Assay≥97% (HPLC)
Colorlight yellow
Formsolid; desiccated; protect from light
Size10MG
Storage Conditions+2C to +8C
1

Adenosine A(2A) Receptor Antagonists and Parkinson's Disease

Brian C Shook, Paul F Jackson

ACS Chem Neurosci. 2011 Oct 19;2(10):555-67.

PMID: 22860156

1

Adenosine A(2A) Receptors Are Necessary and Sufficient to Trigger Memory Impairment in Adult Mice

N Pagnussat, A S Almeida, D M Marques, F Nunes, G C Chenet, P H S Botton, S Mioranzza, C M Loss, R A Cunha, L O Porciúncula

Br J Pharmacol. 2015 Aug;172(15):3831-45.

PMID: 25939452

1

Glucocorticoids Regulate the Expression of Adenosine A1 but Not A(2A) Receptors in Rat Brain

P Svenningsson, B B Fredholm

J Pharmacol Exp Ther. 1997 Feb;280(2):1094-101.

PMID: 9023328

1

In Vivo Characterization of a Dual Adenosine A2A/A1 Receptor Antagonist in Animal Models of Parkinson's Disease

Brian C Shook, Stefanie Rassnick, Melville C Osborne, Scott Davis, Lori Westover, Jamie Boulet, Daniel Hall, Kenneth C Rupert, Geoffrey R Heintzelman, Kristin Hansen, Devraj Chakravarty, James L Bullington, etc.

J Med Chem. 2010 Nov 25;53(22):8104-15.

PMID: 20973483

1

Spinal and Peripheral Adenosine A₁ Receptors Contribute to Antinociception by Tramadol in the Formalin Test in Mice

Jana Sawynok, Allison R Reid, Jean Liu

Eur J Pharmacol. 2013 Aug 15;714(1-3):373-8.

PMID: 23872384

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