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AF-DX 116

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For Research Use Only | Not For Clinical Use
CATAP102394310
CAS102394-31-0
Structure
MDL NumberMFCD00864743
Molecular Weight421.54
InChI KeyUBRKDAVQCKZSPO-UHFFFAOYSA-N
Description≥98% (HPLC)
SolubilityDMSO: 5 mg/mL (clear solution; warmed)
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditionsroom temp
1

[3H]AF-DX 116 Labels Subsets of Muscarinic Cholinergic Receptors in Rat Brain and Heart

J X Wang, W R Roeske, K Gulya, W Wang, H I Yamamura

Life Sci. 1987 Oct 5;41(14):1751-60.

PMID: 3657382

1

AF-DX 116, a Cardioselective Muscarinic Antagonist

R Micheletti, E Montagna, A Giachetti

J Pharmacol Exp Ther. 1987 May;241(2):628-34.

PMID: 2883303

1

Cardioselective Profile of AF-DX 116, a Muscarine M2 Receptor Antagonist

A Giachetti, R Micheletti, E Montagna

Life Sci. 1986 May 5;38(18):1663-72.

PMID: 3754611

1

Comparison of anti-M2-muscarinic Effect of AF-DX 116 on Atrioventricular Nodal Conduction With Those of Pirenzepine and Atropine as Antibradyarrhythmic Drugs

S Sasaki, S Motomura

J Cardiovasc Pharmacol. 1999 Jun;33(6):912-21.

PMID: 10367595

1

The Effects of AF-DX 116, a Cardioselective Muscarinic Antagonist, on the Negative Inotropic Action of Acetylcholine

S I Baskin, R H Thomsen

Res Commun Chem Pathol Pharmacol. 1991 Jan;71(1):3-16.

PMID: 2024064

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