0

AGI-6780

INQUIRY Add to cart
For Research Use Only | Not For Clinical Use
CATAP1432660473
CAS1432660-47-3
Molecular Weight481.51
Description≥98% (HPLC)
SolubilityDMSO: 20 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to light brown
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

Allosteric Inhibitor Remotely Modulates the Conformation of the Orthestric Pockets in Mutant IDH2/R140Q

Jiao Chen, Jie Yang, Xianqiang Sun, Zhongming Wang, Xiaolan Cheng, Wuguang Lu, Xueting Cai, Chunping Hu, Xu Shen, Peng Cao

Sci Rep. 2017 Nov 28;7(1):16458.

PMID: 29184081

1

IDH2 Inhibition Enhances Proteasome Inhibitor Responsiveness in Hematological Malignancies

Elisa Bergaggio, Chiara Riganti, Giulia Garaffo, Nicoletta Vitale, Elisabetta Mereu, Cecilia Bandini, Elisa Pellegrino, Verdiana Pullano, Paola Omedè, Katia Todoerti, Luciano Cascione, Valentina Audrito, etc.

Blood. 2019 Jan 10;133(2):156-167.

PMID: 30455381

1

Targeted Inhibition of Mutant IDH2 in Leukemia Cells Induces Cellular Differentiation

Fang Wang, Jeremy Travins, Byron DeLaBarre, Virginie Penard-Lacronique, Stefanie Schalm, Erica Hansen, Kimberly Straley, Andrew Kernytsky, Wei Liu, Camelia Gliser, Hua Yang, Stefan Gross, Erin Artin, Veronique Saada, etc.

Science. 2013 May 3;340(6132):622-6.

PMID: 23558173

1

The Evolving Landscape in the Development of Isocitrate Dehydrogenase Mutant Inhibitors

Jiao Chen, Jie Yang, Peng Cao

Mini Rev Med Chem. 2016;16(16):1344-1358.

PMID: 27292784

1

Wild-type IDH2 Promotes the Warburg Effect and Tumor Growth Through HIF1α in Lung Cancer

Jiangjiang Li, Ya He, Zheqiong Tan, Jingchen Lu, Liling Li, Xin Song, Feng Shi, Longlong Xie, Shuo You, Xiangjian Luo, Namei Li, Yueshuo Li, Xiaolan Liu, Min Tang, Xinxian Weng, Wei Yi, Jia Fan, Jian Zhou, etc.

Theranostics. 2018 Jul 16;8(15):4050-4061.

PMID: 30128035

  • Verification code
Contact Us

Send Us a Request

What is your specific need? We will do everything we can to meet your expectations.
Online Inquiry

Inquiry

For any inquiry, question or recommendation, please call: or fill out the following form.

  • Verification code

Head Office

  • Tel:
  • Email:

Follow us on

qrcode