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Alsterpaullone

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For Research Use Only | Not For Clinical Use
CATAP237430034-A
CAS237430-03-4
MDL NumberMFCD02683579
Molecular Weight293.28
InChI KeyOLUKILHGKRVDCT-UHFFFAOYSA-N
Description≥98% (HPLC), powder
SolubilityDMSO: ≥10 mg/mL
Assay≥98% (HPLC)
Coloryellow to brown
Formpowder
Size1MG
Storage Conditions2-8°C
1

Alsterpaullone, a Cyclin-Dependent Kinase Inhibitor, Mediated Toxicity in HeLa Cells Through Apoptosis-Inducing Effect

Chunying Cui, Yuji Wang, Yaonan Wang, Ming Zhao, Shiqi Peng

J Anal Methods Chem. 2013;2013:602091.

PMID: 23577282

1

GSK-3β Inhibitor Alsterpaullone Attenuates MPP

Jiancai Wang, Yuqian Li, Li Gao, Fengqi Yan, Guodong Gao, Lihong Li

Front Cell Neurosci. 2018 Aug 30;12:283.

PMID: 30233322

1

High-content Screening Assay-Based Discovery of Paullones as Novel Podocyte-Protective Agents

Ha Won Lee, Ehtesham Arif, Mehmet M Altintas, Kevin Quick, Shrey Maheshwari, Alexandra Plezia, Aqsa Mahmood, Jochen Reiser, Deepak Nihalani, Vineet Gupta

Am J Physiol Renal Physiol. 2018 Feb 1;314(2):F280-F292.

PMID: 29046299

1

Identification of Alsterpaullone as a Novel Small Molecule Inhibitor to Target Group 3 Medulloblastoma

Claudia C Faria, Sameer Agnihotri, Stephen C Mack, Brian J Golbourn, Roberto J Diaz, Samantha Olsen, Melissa Bryant, Matthew Bebenek, Xin Wang, Kelsey C Bertrand, Michelle Kushida, Renee Head, Ian Clark, etc.

Oncotarget. 2015 Aug 28;6(25):21718-29.

PMID: 26061748

1

Poly(ethylene Glycol) Prodrugs of the CDK Inhibitor, Alsterpaullone (NSC 705701): Synthesis and Pharmacokinetic Studies

Richard B Greenwald, Hong Zhao, Jing Xia, Dechun Wu, Stephen Nervi, Sherman F Stinson, Eva Majerova, Chris Bramhall, Daniel W Zaharevitz

Bioconjug Chem. Sep-Oct 2004;15(5):1076-83.

PMID: 15366962

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