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AM4113

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For Research Use Only | Not For Clinical Use
CATAP614726851
CAS614726-85-1
Molecular Weight380.66
Description≥98% (HPLC)
SolubilityDMSO: 2 mg/mL, clear (warmed)
Assay≥98% (HPLC)
Colorwhite to brown
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

A Neutral CB1 Receptor Antagonist Reduces Weight Gain in Rat

Adam P Chambers, V Kiran Vemuri, Yan Peng, Jodianne T Wood, Teresa Olszewska, Quentin J Pittman, Alexandros Makriyannis, Keith A Sharkey

Am J Physiol Regul Integr Comp Physiol. 2007 Dec;293(6):R2185-93.

PMID: 17959701

1

Cannabinoid-1 Receptor Neutral Antagonist Reduces Binge-Like Alcohol Consumption and Alcohol-Induced Accumbal Dopaminergic Signaling

Andrea Balla, Bin Dong, Borehalli M Shilpa, Kiran Vemuri, Alexandros Makriyannis, Subhash C Pandey, Henry Sershen, Raymond F Suckow, K Yaragudri Vinod

Neuropharmacology. 2018 Mar 15;131:200-208.

PMID: 29109060

1

CB1 Antagonism: Interference With Affective Properties of Acute Naloxone-Precipitated Morphine Withdrawal in Rats

Kiri L Wills, Kiran Vemuri, Alana Kalmar, Alan Lee, Cheryl L Limebeer, Alexandros Makriyannis, Linda A Parker

Psychopharmacology (Berl). 2014 Nov;231(22):4291-300.

PMID: 24770676

1

Potential of Cannabinoid Receptor Ligands as Treatment for Substance Use Disorders

Ewa Galaj, Zheng-Xiong Xi

CNS Drugs. 2019 Oct;33(10):1001-1030.

PMID: 31549358

1

The CB1 Neutral Antagonist AM4113 Retains the Therapeutic Efficacy of the Inverse Agonist Rimonabant for Nicotine Dependence and Weight Loss With Better Psychiatric Tolerability

Aliou B Gueye, Yaroslaw Pryslawsky, Jose M Trigo, Nafsika Poulia, Foteini Delis, Katerina Antoniou, Michael Loureiro, Steve R Laviolette, Kiran Vemuri, Alexandros Makriyannis, Bernard Le Foll

Int J Neuropsychopharmacol. 2016 Dec 30;19(12):pyw068.

PMID: 27493155

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