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AMG 9810

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For Research Use Only | Not For Clinical Use
CATAP545395946
CAS545395-94-6
Structure
MDL NumberMFCD00955103
Molecular Weight337.41
InChI KeyGZTFUVZVLYUPRG-IZZDOVSWSA-N
Description≥98% (HPLC), powder
SolubilityDMSO: >5 mg/mL
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size10MG, 50MG
Storage Conditions2-8°C
1

AMG 9810 [(E)-3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo[b][1,4] dioxin-6-yl)acrylamide], a Novel Vanilloid Receptor 1 (TRPV1) Antagonist With Antihyperalgesic Properties

Narender R Gavva, Rami Tamir, Yusheng Qu, Lana Klionsky, T J Zhang, David Immke, Judy Wang, Dawn Zhu, Todd W Vanderah, Frank Porreca, Elizabeth M Doherty, Mark H Norman, Kenneth D Wild, Anthony W Bannon, etc.

J Pharmacol Exp Ther. 2005 Apr;313(1):474-84.

PMID: 15615864

1

Do TRPV1 Antagonists Increase the Risk for Skin Tumourigenesis? A Collaborative in Vitro and in Vivo Assessment

Miyoung Park, Anita A Naidoo, Angie Burns, Jin Kyu Choi, Kelly M Gatfield, Martin Vidgeon-Hart, Il-Hong Bae, Chang Seok Lee, Gyeyoung Choi, Andrew J Powell, Young-Ho Park, Rajni Fagg

Cell Biol Toxicol. 2018 Apr;34(2):143-162.

PMID: 28815372

1

Endocannabinoid System and TRPV1 Receptors in the Dorsal Hippocampus of the Rats Modulate Anxiety-like Behaviors

Elham Hakimizadeh, Shahrbanoo Oryan, Akbar Hajizadeh Moghaddam, Ali Shamsizadeh, Ali Roohbakhsh

Iran J Basic Med Sci. 2012 May;15(3):795-802.

PMID: 23493622

1

Increased Asics Expression via the Camkii-CREB Pathway in a Novel Mouse Model of Trigeminal Pain

Yan Wang, Xiujuan Fu, Lifang Huang, Xi Wang, Zuneng Lu, Fan Zhu, Zheman Xiao

Cell Physiol Biochem. 2018;46(2):568-578.

PMID: 29617678

1

Vagal TRPV1 Activation Exacerbates Thermal Hyperpnea and Increases Susceptibility to Experimental Febrile Seizures in Immature Rats

Karlene T Barrett, Arijit Roy, Keelin B Rivard, Richard J A Wilson, Morris H Scantlebury

Neurobiol Dis. 2018 Nov;119:172-189.

PMID: 30121230

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