Amyloid Precursor Protein α (304-612), Secreted human - Analytical Products / Alfa Chemistry

CAT	IAR4248084
MDL Number	MFCD03791389

Description	>90% (SDS-PAGE), recombinant, expressed in E. coli (N-terminal histidine tagged), buffered aqueous solution
Assay	>90% (SDS-PAGE)
Form	buffered aqueous solution
Size	25μG
Storage Conditions	−70°C

1

Amyloid Precursor Protein Expression and Processing Are Differentially Regulated During Cortical Neuron Differentiation

Petra Bergström, Lotta Agholme, Faisal Hayat Nazir, Tugce Munise Satir, Jamie Toombs, Henrietta Wellington, Joakim Strandberg, Thomas Olsson Bontell, Hlin Kvartsberg, Maria Holmström, Cecilia Boreström, etc.

Sci Rep. 2016 Jul 7;6:29200.

PMID: 27383650

1

Amyloid Precursor Protein Products Concentrate in a Subset of Exosomes Specifically Endocytosed by Neurons

Karine Laulagnier, Charlotte Javalet, Fiona J Hemming, Mathilde Chivet, Gaëlle Lachenal, Béatrice Blot, Christine Chatellard, Rémy Sadoul

Cell Mol Life Sci. 2018 Feb;75(4):757-773.

PMID: 28956068

1

Astrocytes Regulate α-secretase-cleaved Soluble Amyloid Precursor Protein Secretion in Neuronal Cells: Involvement of Group IIA Secretory Phospholipase A2

X Yang, W Sheng, D M Ridgley, M A Haidekker, G Y Sun, J C Lee

Neuroscience. 2015 Aug 6;300:508-17.

PMID: 26037803

1

Brain Endothelial Cells Produce Amyloid {beta} From Amyloid Precursor Protein 770 and Preferentially Secrete the O-glycosylated Form

Shinobu Kitazume, Yuriko Tachida, Masaki Kato, Yoshiki Yamaguchi, Takashi Honda, Yasuhiro Hashimoto, Yoshinao Wada, Takashi Saito, Nobuhisa Iwata, Takaomi Saido, Naoyuki Taniguchi

J Biol Chem. 2010 Dec 17;285(51):40097-103.

PMID: 20952385

1

Lentivirus-mediated Expression of Human Secreted Amyloid Precursor Protein-Alpha Prevents Development of Memory and Plasticity Deficits in a Mouse Model of Alzheimer's Disease

Valerie T Y Tan, Bruce G Mockett, Shane M Ohline, Karen D Parfitt, Hollie E Wicky, Katie Peppercorn, Lucia Schoderboeck, Mohamad Fairuz Bin Yahaya, Warren P Tate, Stephanie M Hughes, Wickliffe C Abraham

Mol Brain. 2018 Feb 9;11(1):7.

PMID: 29426354

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