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Apicidin, Fusarium sp.

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For Research Use Only | Not For Clinical Use
CATIAR42415437
Molecular Weight623.78
DescriptionA potent, cell-permeable inhibitor of histone deacetylase (IC₅₀= 700 pM for parasitic histone deactetylase) that also exibits antiprotozoal and potential anti-malarial properties.
SolubilityDMSO: 50 mg/mL; ethanol: soluble
Assay≥95% (HPLC)
Colorwhite
Formsolid; protect from light
Size1MG, 5MG
Storage Conditions-20C
1

A Hemorrhagic Factor (Apicidin) Produced by Toxic Fusarium Isolates From Soybean Seeds

J S Park, K R Lee, J C Kim, S H Lim, J A Seo, Y W Lee

Appl Environ Microbiol. 1999 Jan;65(1):126-30.

PMID: 9872769

1

Apicidin Inhibited Proliferation and Invasion and Induced Apoptosis via Mitochondrial Pathway in Non-small Cell Lung Cancer GLC-82 Cells

Jianye Zhang, Zhenzhu Lai, Wenjing Huang, Huiping Ling, Minting Lin, Sili Tang, Yun Liu, Yiwen Tao

Anticancer Agents Med Chem. 2017;17(10):1374-1382.

PMID: 28425856

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