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ApoE2 human

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For Research Use Only | Not For Clinical Use
CATIAR4247086
MDL NumberMFCD00285513
Descriptionrecombinant, expressed in E. coli, ≥90% (SDS-PAGE), ≥90% (HPLC)
Assay≥90% (HPLC); ≥90% (SDS-PAGE)
Formlyophilized
Impurity Contentendotoxin, tested
Size500μG
Storage Conditions−20°C
1

AAVrh.10-Mediated APOE2 Central Nervous System Gene Therapy for APOE4-Associated Alzheimer's Disease

Jonathan B Rosenberg, Michael G Kaplitt, Bishnu P De, Alvin Chen, Thomas Flagiello, Christiana Salami, Eduard Pey, Lingzhi Zhao, Rodolfo J Ricart Arbona, Sebastien Monette, Jonathan P Dyke, Douglas J Ballon, etc.

Hum Gene Ther Clin Dev. 2018 Mar;29(1):24-47.

PMID: 29409358

1

ApoE and Neurodegenerative Diseases in Aging

Yuemiao Yin, Zhao Wang

Adv Exp Med Biol. 2018;1086:77-92.

PMID: 30232753

1

Apolipoprotein E Controls Cerebrovascular Integrity via Cyclophilin A

Robert D Bell, Ethan A Winkler, Itender Singh, Abhay P Sagare, Rashid Deane, Zhenhua Wu, David M Holtzman, Christer Betsholtz, Annika Armulik, Jan Sallstrom, Bradford C Berk, Berislav V Zlokovic

Nature. 2012 May 16;485(7399):512-6.

PMID: 22622580

1

Differential Signaling Mediated by ApoE2, ApoE3, and ApoE4 in Human Neurons Parallels Alzheimer's Disease Risk

Yu-Wen Alvin Huang, Bo Zhou, Amber M Nabet, Marius Wernig, Thomas C Südhof

J Neurosci. 2019 Sep 11;39(37):7408-7427.

PMID: 31331998

1

The Glia-Neuron Lactate Shuttle and Elevated ROS Promote Lipid Synthesis in Neurons and Lipid Droplet Accumulation in Glia via APOE/D

Lucy Liu, Kevin R MacKenzie, Nagireddy Putluri, Mirjana Maletić-Savatić, Hugo J Bellen

Cell Metab. 2017 Nov 7;26(5):719-737.e6.

PMID: 28965825

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