Apolipoprotein A−I human - Analytical Products / Alfa Chemistry

CAT

IAR4247083

Description	recombinant, expressed in E. coli, ≥97% (SDS-PAGE), ≥97% (HPLC)
Assay	≥97% (HPLC); ≥97% (SDS-PAGE)
Form	lyophilized
Impurity Content	endotoxin, tested
Size	100μG
Storage Conditions	−20°C

1

Cholesterol Efflux, Lecithin-Cholesterol Acyltransferase Activity, and Pre-Beta Particle Formation by Serum From Human Apolipoprotein A-I and Apolipoprotein A-I/apolipoprotein A-II Transgenic Mice Consistent With the Latter Being Less Effective for Reverse Cholesterol Transport

G Castro, L P Nihoul, C Dengremont, C de Geitère, B Delfly, A Tailleux, C Fievet, N Duverger, P Denèfle, J C Fruchart, E M Rubin

Biochemistry. 1997 Feb 25;36(8):2243-9.

PMID: 9047326

1

CSL112 (Apolipoprotein A-I [Human]) Enhances Cholesterol Efflux Similarly in Healthy Individuals and Stable Atherosclerotic Disease Patients

Andreas Gille, Denise D'Andrea, Michael A Tortorici, Gunter Hartel, Samuel D Wright

Arterioscler Thromb Vasc Biol. 2018 Apr;38(4):953-963.

PMID: 29437574

1

Evaluation of Potential Antiplatelet Effects of CSL112 (Apolipoprotein A-I [Human]) in Patients With Atherosclerosis: Results From a Phase 2a Study

Paul A Gurbel, Udaya S Tantry, Denise D'Andrea, Thomas Chung, John H Alexander, Kevin P Bliden, Samuel D Wright, Pierluigi Tricoci

J Thromb Thrombolysis. 2018 May;45(4):469-476.

PMID: 29582212

1

Pharmacokinetics and Safety of CSL112 (Apolipoprotein A-I [Human]) in Adults With Moderate Renal Impairment and Normal Renal Function

Michael A Tortorici, Danielle Duffy, Rebecca Evans, John Feaster, Andreas Gille, Timothy G K Mant, Samuel D Wright, Denise D'Andrea

Clin Pharmacol Drug Dev. 2019 Jul;8(5):628-636.

PMID: 30240132

1

The CSL112-2001 Trial: Safety and Tolerability of Multiple Doses of CSL112 (Apolipoprotein A-I [Human]), an Intravenous Formulation of Plasma-Derived Apolipoprotein A-I, Among Subjects With Moderate Renal Impairment After Acute Myocardial Infarction

C Michael Gibson, Mathieu Kerneis, Megan K Yee, Yazan Daaboul, Serge Korjian, Ali Poyan Mehr, Pierluigi Tricoci, John H Alexander, John J P Kastelein, Roxana Mehran, Christoph Bode, Basil S Lewis, Ravindra Mehta, etc.

Am Heart J. 2019 Feb;208:81-90.

PMID: 30580130

* Products or Services Interested: Apolipoprotein A−I human ()
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