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Apolipoprotein E4 human

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For Research Use Only | Not For Clinical Use
CATIAR4247071
MDL NumberMFCD00285515
Descriptionrecombinant, expressed in E. coli, ≥90% (SDS-PAGE and HPLC), lyophilized powder
Assay≥90% (SDS-PAGE and HPLC)
Formlyophilized powder
Size100μG
Storage Conditions−20°C
1

A Quarter Century of APOE and Alzheimer's Disease: Progress to Date and the Path Forward

Michaël E Belloy, Valerio Napolioni, Michael D Greicius

Neuron. 2019 Mar 6;101(5):820-838.

PMID: 30844401

1

APOE4 Causes Widespread Molecular and Cellular Alterations Associated With Alzheimer's Disease Phenotypes in Human iPSC-Derived Brain Cell Types

Yuan-Ta Lin, Jinsoo Seo, Fan Gao, Heather M Feldman, Hsin-Lan Wen, Jay Penney, Hugh P Cam, Elizabeta Gjoneska, Waseem K Raja, Jemmie Cheng, Richard Rueda, Oleg Kritskiy, Fatema Abdurrob, Zhuyu Peng, Blerta Milo, etc.

Neuron. 2018 Jun 27;98(6):1141-1154.e7.

PMID: 29861287

1

ApoE4 Markedly Exacerbates Tau-Mediated Neurodegeneration in a Mouse Model of Tauopathy

Yang Shi, Kaoru Yamada, Shane Antony Liddelow, Scott T Smith, Lingzhi Zhao, Wenjie Luo, Richard M Tsai, Salvatore Spina, Lea T Grinberg, Julio C Rojas, Gilbert Gallardo, Kairuo Wang, Joseph Roh, Grace Robinson, etc.

Nature. 2017 Sep 28;549(7673):523-527.

PMID: 28959956

1

Apolipoprotein E4 Genotype Compromises Brain Exosome Production

Katherine Y Peng, Rocío Pérez-González, Melissa J Alldred, Chris N Goulbourne, Jose Morales-Corraliza, Mariko Saito, Mitsuo Saito, Stephen D Ginsberg, Paul M Mathews, Efrat Levy

Brain. 2019 Jan 1;142(1):163-175.

PMID: 30496349

1

Gain of Toxic Apolipoprotein E4 Effects in Human iPSC-derived Neurons Is Ameliorated by a Small-Molecule Structure Corrector

Chengzhong Wang, Ramsey Najm, Qin Xu, Dah-Eun Jeong, David Walker, Maureen E Balestra, Seo Yeon Yoon, Heidi Yuan, Gang Li, Zachary A Miller, Bruce L Miller, Mary J Malloy, Yadong Huang

Nat Med. 2018 May;24(5):647-657.

PMID: 29632371

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