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APX2009

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For Research Use Only | Not For Clinical Use
CATIAR4242351
Molecular Weight355.43
Description≥98% (HPLC)
SolubilityDMSO: 10 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

APE1/Ref-1 Redox-Specific Inhibition Decreases Survivin Protein Levels and Induces Cell Cycle Arrest in Prostate Cancer Cells

David W McIlwain, Melissa L Fishel, Alexander Boos, Mark R Kelley, Travis J Jerde

Oncotarget. 2017 Dec 13;9(13):10962-10977.

PMID: 29541389

1

Identification and Characterization of New Chemical Entities Targeting Apurinic/Apyrimidinic Endonuclease 1 for the Prevention of Chemotherapy-Induced Peripheral Neuropathy

Mark R Kelley, James H Wikel, Chunlu Guo, Karen E Pollok, Barbara J Bailey, Randy Wireman, Melissa L Fishel, Michael R Vasko

J Pharmacol Exp Ther. 2016 Nov;359(2):300-309.

PMID: 27608656

1

Ref-1/APE1 Inhibition With Novel Small Molecules Blocks Ocular Neovascularization

Sheik Pran Babu Sardar Pasha, Kamakshi Sishtla, Rania S Sulaiman, Bomina Park, Trupti Shetty, Fenil Shah, Melissa L Fishel, James H Wikel, Mark R Kelley, Timothy W Corson

J Pharmacol Exp Ther. 2018 Oct;367(1):108-118.

PMID: 30076264

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