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AR-A014418

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For Research Use Only | Not For Clinical Use
CATAP487021523-A
CAS487021-52-3
Structure
MDL NumberMFCD08277040
Molecular Weight308.31
InChI KeyYAEMHJKFIIIULI-UHFFFAOYSA-N
Description≥98% (HPLC), solid
SolubilityDMSO: ≥20 mg/mL, clear, light yellow; H2O: insoluble
Assay≥98% (HPLC)
Coloroff-white to tan
Formsolid
Size5MG, 25MG
Storage Conditions2-8°C
1

AR-A014418 as a Glycogen Synthase kinase-3 Inhibitor: Anti-Apoptotic and Therapeutic Potential in Experimental Spinal Cord Injury

Matem Tunçdemir, Aziz Yıldırım, Alper Karaoğlan, Osman Akdemir, Melek Oztürk

Neurocirugia (Astur). Jan-Feb 2013;24(1):22-32.

PMID: 23116585

1

AR-A014418, a Selective GSK-3 Inhibitor, Produces Antidepressant-Like Effects in the Forced Swim Test

Todd D Gould, Haim Einat, Ratan Bhat, Husseini K Manji

Int J Neuropsychopharmacol. 2004 Dec;7(4):387-90.

PMID: 15315719

1

Glycogen Synthase Kinase 3-specific Inhibitor AR-A014418 Decreases Neuropathic Pain in Mice: Evidence for the Mechanisms of Action

L Mazzardo-Martins, D F Martins, J Stramosk, F J Cidral-Filho, A R S Santos

Neuroscience. 2012 Dec 13;226:411-20.

PMID: 23000630

1

GSK3 Inhibitor AR-A014418 Promotes Osteogenic Differentiation of Human Adipose-Derived Stem Cells via ERK and mTORC2/Akt Signaling Pathway

Min Zhang, Ping Zhang, Yunsong Liu, Yongsheng Zhou

Biochem Biophys Res Commun. 2017 Aug 19;490(2):182-188.

PMID: 28602697

1

The Antinociceptive Effects of AR-A014418, a Selective Inhibitor of Glycogen Synthase kinase-3 Beta, in Mice

Daniel F Martins, Angelo O Rosa, Vinícius M Gadotti, Leidiane Mazzardo-Martins, Francisney P Nascimento, Javier Egea, Manuela G López, Adair R S Santos

J Pain. 2011 Mar;12(3):315-22.

PMID: 20705523

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