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Arachidonyl trifluoromethyl ketone

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For Research Use Only | Not For Clinical Use
CATAP149301791
CAS149301-79-1
Structure
MDL NumberMFCD00236427
Molecular Weight356.47
InChI KeyPLWROONZUDKYKG-DOFZRALJSA-N
Descriptionoil, ≥97% (NMR)
SolubilityDMSO: >5 mg/mL
Assay≥97% (NMR)
Coloryellow
Formoil; protect from light; under inert gas
Size5MG
Storage Conditions−20°C
1

Arachidonyl Trifluoromethyl Ketone Ameliorates Experimental Autoimmune Encephalomyelitis via Blocking Peroxynitrite Formation in Mouse Spinal Cord White Matter

Adam C Vana, Shihe Li, Rachel Ribeiro, Flaubert Tchantchou, Yumin Zhang

Exp Neurol. 2011 Sep;231(1):45-55.

PMID: 21683698

1

Arachidonyl Trifluoromethyl Ketone Induces Lipid Body Formation in Leukocytes

P T Bozza, P F Weller

Prostaglandins Leukot Essent Fatty Acids. Apr-May 2001;64(4-5):227-30.

PMID: 11418016

1

Arachidonyl Trifluoromethyl Ketone Is Neuroprotective After Spinal Cord Injury

Wenlong Huang, Amar Bhavsar, Rachael E Ward, Jodie C E Hall, John V Priestley, Adina T Michael-Titus

J Neurotrauma. 2009 Aug;26(8):1429-34.

PMID: 19371144

1

Arachidonyl Trifluoromethyl Ketone, a Potent Inhibitor of 85-kDa Phospholipase A2, Blocks Production of Arachidonate and 12-hydroxyeicosatetraenoic Acid by Calcium Ionophore-Challenged Platelets

D Riendeau, J Guay, P K Weech, F Laliberté, J Yergey, C Li, S Desmarais, H Perrier, S Liu, D Nicoll-Griffith

J Biol Chem. 1994 Jun 3;269(22):15619-24.

PMID: 8195210

1

Oral Administration of Cytosolic PLA2 Inhibitor Arachidonyl Trifluoromethyl Ketone Ameliorates Cauda Equina Compression Injury in Rats

Mushfiquddin Khan, Anandakumar Shunmugavel, Tajinder S Dhammu, Fumiyo Matsuda, Avtar K Singh, Inderjit Singh

J Neuroinflammation. 2015 May 15;12:94.

PMID: 25971887

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