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Ascochlorin

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For Research Use Only | Not For Clinical Use
CATAP26166392
CAS26166-39-2
Structure
Molecular Weight404.93
Description≥98% (HPLC), from Verticillium hemipterigenum
SolubilityDMSO: soluble; H2O: insoluble; chloroform: soluble; ethyl acetate: soluble; methanol: soluble
Assay≥98% (HPLC)
Size500UG
Storage Conditions−20°C
1

4- O-methylascochlorin stabilizes hypoxia-inducible factor-1 in a manner different from hydroxylase inhibition by iron chelating or substrate competition

Junji Magae, Chiharu Furukawa, Shigefumi Kuwahara, Yun-Jeong Jeong, Hiroo Nakajima, Young-Chae Chang

Biosci Biotechnol Biochem. 2019 Dec;83(12):2244-2248.

PMID: 31392931

1

Ascochlorin Induces Caspase-Independent Necroptosis in LPS-stimulated RAW 264.7 Macrophages

Junyoung Park, Hee-Do Kim, Sook-Hyun Lee, Choong-Hwan Kwak, Young-Chae Chang, Young-Choon Lee, Tae-Wook Chung, Junji Magae, Cheorl-Ho Kim

J Ethnopharmacol. 2019 Jul 15;239:111898.

PMID: 31028855

1

Ascochlorin Is a Novel, Specific Inhibitor of the Mitochondrial Cytochrome bc1 Complex

Edward A Berry, Li-Shar Huang, Dong-Woo Lee, Fevzi Daldal, Kazuo Nagai, Nobuko Minagawa

Biochim Biophys Acta. 2010 Mar;1797(3):360-70.

PMID: 20025846

1

Complete biosynthetic pathways of ascofuranone and ascochlorin in Acremonium egyptiacum

Yasuko Araki, Takayoshi Awakawa, Motomichi Matsuzaki, Rihe Cho, Yudai Matsuda, Shotaro Hoshino, Yasutomo Shinohara, Masaichi Yamamoto, Yasutoshi Kido, Daniel Ken Inaoka, Kisaburo Nagamune, Kotaro Ito, Ikuro Abe, etc.

Proc Natl Acad Sci U S A. 2019 Apr 23;116(17):8269-8274.

PMID: 30952781

1

Suppression of c-Myc enhances p21 WAF1/CIP1 -mediated G1 cell cycle arrest through the modulation of ERK phosphorylation by ascochlorin

Yun-Jeong Jeong, Hyang-Sook Hoe, Hyun-Ji Cho, Kwan-Kyu Park, Dae-Dong Kim, Cheorl-Ho Kim, Junji Magae, Dong Wook Kang, Sang-Rae Lee, Young-Chae Chang

J Cell Biochem. 2018 Feb;119(2):2036-2047.

PMID: 28833404

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